LE RISPOSTE EVOCATE VISIVE SOTTO STIMOLAZIONE A DI VERA LUNGHEZZA D'ONDA NELLA DIAGNOSI PRECOCE DELLA SCLEROSI A PLACCHE

An examination was made up of 40 patients by possible, probable and certain multiple sclerosis according to the classification of Macchi. These have been compared with patients who complained of other anomalies of neurological type and with a control group of normal subjects. The visual evoked potentials were obtained with white and red flashes at casual frequency and with repetitive stimuli at 16 and 40 Hz. In 25 patients with multiple sclerosis, that was certain the latency at the peak of the four occipital components was significantly delayed. Of 8 subjects with the spinal localized forms, 4 showed anomalous responses. 20 subjects were examined before during and after the treatment cycle. The visual symptoms, not depending on the presence of demonstrable campimetric defects. In the author's cases, the latencies were increased (over 70 msec at the first peak), and the amplitude diminished to such a degree as sometimes to make it difficult to identify the waves. The incidence of anomalous responses was greater after stimulation with red light and in the group with certain multiple sclerosis. All of the patients with unilateral retrobulbar neuritis showed an assymmetry of the visual evoked potentials (more than 5 msec) either between the 2 occipital leads or between the two eyes.