Visual evoked potentials in patients with neuropathy and macroglobulinemia

S. Barbieri, E. Nobile-Orazio, L. Baldini, Z. Fayoumi, E. Manfredini, G. Scarlato

Research output: Contribution to journalArticlepeer-review


Visual evoked potentials were studied in 11 patients with neuropathy and macroglobulinemia. The P100 latency was increased bilaterally in 5 of the 6 patients whose IgM M-proteins reacted with myelin-associated glycoprotein (MAG) and in 1 of the other patients. In patients whose M-protein bound to MAG, abnormal visual evoked potentials correlated with the presence of the M-protein in the cerebrospinal fluid. Subclinical involvement of the central nervous system is frequent in patients with neuropathy and anti-MAG M-proteins and may be due to the binding of M-proteins to central nervous system myelin.

Original languageEnglish
Pages (from-to)663-666
Number of pages4
JournalAnnals of Neurology
Issue number5
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Neuroscience(all)


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