Visual evoked potentials in patients with neuropathy and macroglobulinemia

S. Barbieri, E. Nobile-Orazio, L. Baldini, Z. Fayoumi, E. Manfredini, G. Scarlato

Research output: Contribution to journalArticle

Abstract

Visual evoked potentials were studied in 11 patients with neuropathy and macroglobulinemia. The P100 latency was increased bilaterally in 5 of the 6 patients whose IgM M-proteins reacted with myelin-associated glycoprotein (MAG) and in 1 of the other patients. In patients whose M-protein bound to MAG, abnormal visual evoked potentials correlated with the presence of the M-protein in the cerebrospinal fluid. Subclinical involvement of the central nervous system is frequent in patients with neuropathy and anti-MAG M-proteins and may be due to the binding of M-proteins to central nervous system myelin.

Original languageEnglish
Pages (from-to)663-666
Number of pages4
JournalAnnals of Neurology
Volume22
Issue number5
Publication statusPublished - 1987

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Waldenstrom Macroglobulinemia
Visual Evoked Potentials
Myelin-Associated Glycoprotein
Central Nervous System
Cerebrospinal Fluid Proteins
Proteins
Myelin Sheath
Immunoglobulin M
Carrier Proteins

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Visual evoked potentials in patients with neuropathy and macroglobulinemia. / Barbieri, S.; Nobile-Orazio, E.; Baldini, L.; Fayoumi, Z.; Manfredini, E.; Scarlato, G.

In: Annals of Neurology, Vol. 22, No. 5, 1987, p. 663-666.

Research output: Contribution to journalArticle

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AU - Scarlato, G.

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