Abstract
Visual evoked potentials were studied in 11 patients with neuropathy and macroglobulinemia. The P100 latency was increased bilaterally in 5 of the 6 patients whose IgM M-proteins reacted with myelin-associated glycoprotein (MAG) and in 1 of the other patients. In patients whose M-protein bound to MAG, abnormal visual evoked potentials correlated with the presence of the M-protein in the cerebrospinal fluid. Subclinical involvement of the central nervous system is frequent in patients with neuropathy and anti-MAG M-proteins and may be due to the binding of M-proteins to central nervous system myelin.
Original language | English |
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Pages (from-to) | 663-666 |
Number of pages | 4 |
Journal | Annals of Neurology |
Volume | 22 |
Issue number | 5 |
Publication status | Published - 1987 |
ASJC Scopus subject areas
- Neuroscience(all)