Visual evoked potentials in patients with neuropathy and macroglobulinemia

S. Barbieri; E. Nobile-Orazio; L. Baldini; Z. Fayoumi; E. Manfredini; G. Scarlato

Visual evoked potentials in patients with neuropathy and macroglobulinemia

S. Barbieri, E. Nobile-Orazio, L. Baldini, Z. Fayoumi, E. Manfredini, G. Scarlato

Research output: Contribution to journal › Article › peer-review

Abstract

Visual evoked potentials were studied in 11 patients with neuropathy and macroglobulinemia. The P100 latency was increased bilaterally in 5 of the 6 patients whose IgM M-proteins reacted with myelin-associated glycoprotein (MAG) and in 1 of the other patients. In patients whose M-protein bound to MAG, abnormal visual evoked potentials correlated with the presence of the M-protein in the cerebrospinal fluid. Subclinical involvement of the central nervous system is frequent in patients with neuropathy and anti-MAG M-proteins and may be due to the binding of M-proteins to central nervous system myelin.

Original language	English
Pages (from-to)	663-666
Number of pages	4
Journal	Annals of Neurology
Volume	22
Issue number	5
Publication status	Published - 1987

ASJC Scopus subject areas

Neuroscience(all)

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abstract = "Visual evoked potentials were studied in 11 patients with neuropathy and macroglobulinemia. The P100 latency was increased bilaterally in 5 of the 6 patients whose IgM M-proteins reacted with myelin-associated glycoprotein (MAG) and in 1 of the other patients. In patients whose M-protein bound to MAG, abnormal visual evoked potentials correlated with the presence of the M-protein in the cerebrospinal fluid. Subclinical involvement of the central nervous system is frequent in patients with neuropathy and anti-MAG M-proteins and may be due to the binding of M-proteins to central nervous system myelin.",

author = "S. Barbieri and E. Nobile-Orazio and L. Baldini and Z. Fayoumi and E. Manfredini and G. Scarlato",

year = "1987",

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T1 - Visual evoked potentials in patients with neuropathy and macroglobulinemia

AU - Barbieri, S.

AU - Nobile-Orazio, E.

AU - Baldini, L.

AU - Fayoumi, Z.

AU - Manfredini, E.

AU - Scarlato, G.

PY - 1987

Y1 - 1987

N2 - Visual evoked potentials were studied in 11 patients with neuropathy and macroglobulinemia. The P100 latency was increased bilaterally in 5 of the 6 patients whose IgM M-proteins reacted with myelin-associated glycoprotein (MAG) and in 1 of the other patients. In patients whose M-protein bound to MAG, abnormal visual evoked potentials correlated with the presence of the M-protein in the cerebrospinal fluid. Subclinical involvement of the central nervous system is frequent in patients with neuropathy and anti-MAG M-proteins and may be due to the binding of M-proteins to central nervous system myelin.

AB - Visual evoked potentials were studied in 11 patients with neuropathy and macroglobulinemia. The P100 latency was increased bilaterally in 5 of the 6 patients whose IgM M-proteins reacted with myelin-associated glycoprotein (MAG) and in 1 of the other patients. In patients whose M-protein bound to MAG, abnormal visual evoked potentials correlated with the presence of the M-protein in the cerebrospinal fluid. Subclinical involvement of the central nervous system is frequent in patients with neuropathy and anti-MAG M-proteins and may be due to the binding of M-proteins to central nervous system myelin.

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EP - 666

JO - Annals of Neurology

JF - Annals of Neurology

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