Abstract
Epileptic photosensitivity is usually associated with generalized epileptogenesis, and is included with few exceptions among idiopathic generalized epilepsies. However, in at least 20% of patients, photic-induced seizures are focal, originating from reflex activation of the occipital cortex. Various anomalies in flash (F) and pattern reversal (PR) visual evoked potentials (VEPs) have been described in generalized photosensitive epilepsy. No data are available on VEPs in patients with photosensitive occipital lobe epilepsy (POE). We investigated PR- and F-VEPs in POE and compared them to responses obtained in patients with idiopathic generalized epilepsy with photosensitivity (IGEP) and in controls. Patients with POE had both a significant increase in VEP amplitude and normal latency. Antiepileptic drugs having gabaergic activity reduced VEP amplitude. IGEP patients showed a significant increase in F-VEP amplitude and reduced P100 latency. Our data indicate the presence of hyperexcitability of occipital cortex in POE. Careful study of VEPs prior to and during treatment with gabaergic drugs represents a useful complemental test to EEG in the assessment of photosensitive epilepsies.
| Original language | Italian |
|---|---|
| Pages (from-to) | 355-358 |
| Number of pages | 4 |
| Journal | Bollettino - Lega Italiana contro l'Epilessia |
| Issue number | 99 |
| Publication status | Published - 1997 |
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ASJC Scopus subject areas
- Clinical Neurology
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Potenziali evocati visivi nelle epilessie occipitali fotosensibili. / Guerrini, R.; Bonanni, P.
In: Bollettino - Lega Italiana contro l'Epilessia, No. 99, 1997, p. 355-358.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Potenziali evocati visivi nelle epilessie occipitali fotosensibili
AU - Guerrini, R.
AU - Bonanni, P.
PY - 1997
Y1 - 1997
N2 - Epileptic photosensitivity is usually associated with generalized epileptogenesis, and is included with few exceptions among idiopathic generalized epilepsies. However, in at least 20% of patients, photic-induced seizures are focal, originating from reflex activation of the occipital cortex. Various anomalies in flash (F) and pattern reversal (PR) visual evoked potentials (VEPs) have been described in generalized photosensitive epilepsy. No data are available on VEPs in patients with photosensitive occipital lobe epilepsy (POE). We investigated PR- and F-VEPs in POE and compared them to responses obtained in patients with idiopathic generalized epilepsy with photosensitivity (IGEP) and in controls. Patients with POE had both a significant increase in VEP amplitude and normal latency. Antiepileptic drugs having gabaergic activity reduced VEP amplitude. IGEP patients showed a significant increase in F-VEP amplitude and reduced P100 latency. Our data indicate the presence of hyperexcitability of occipital cortex in POE. Careful study of VEPs prior to and during treatment with gabaergic drugs represents a useful complemental test to EEG in the assessment of photosensitive epilepsies.
AB - Epileptic photosensitivity is usually associated with generalized epileptogenesis, and is included with few exceptions among idiopathic generalized epilepsies. However, in at least 20% of patients, photic-induced seizures are focal, originating from reflex activation of the occipital cortex. Various anomalies in flash (F) and pattern reversal (PR) visual evoked potentials (VEPs) have been described in generalized photosensitive epilepsy. No data are available on VEPs in patients with photosensitive occipital lobe epilepsy (POE). We investigated PR- and F-VEPs in POE and compared them to responses obtained in patients with idiopathic generalized epilepsy with photosensitivity (IGEP) and in controls. Patients with POE had both a significant increase in VEP amplitude and normal latency. Antiepileptic drugs having gabaergic activity reduced VEP amplitude. IGEP patients showed a significant increase in F-VEP amplitude and reduced P100 latency. Our data indicate the presence of hyperexcitability of occipital cortex in POE. Careful study of VEPs prior to and during treatment with gabaergic drugs represents a useful complemental test to EEG in the assessment of photosensitive epilepsies.
KW - Photosensitive epilepsy
KW - Visual evoked potentials
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UR - http://www.scopus.com/inward/citedby.url?scp=0031429532&partnerID=8YFLogxK
M3 - Articolo
AN - SCOPUS:0031429532
SP - 355
EP - 358
JO - Bollettino - Lega Italiana contro l'Epilessia
JF - Bollettino - Lega Italiana contro l'Epilessia
SN - 0394-560X
IS - 99
ER -