Abstract
PURPOSE: To evaluate visual function variations in eyes with age-related macular degeneration (AMD) compared to normal eyes under different light/contrast conditions using a time-dependent visual acuity testing instrument, the Central Vision Analyzer (CVA).
METHODS: Overall, 37 AMD eyes and 35 normal eyes were consecutively tested with the CVA after assessing best-corrected visual acuity (BCVA) using ETDRS charts. The CVA established visual thresholds for three mesopic environments (M1 (high contrast), M2 (medium contrast), and M3 (low contrast)) and three backlight-glare environments (G1 (high contrast, equivalent to ETDRS), G2 (medium contrast), and G3 (low contrast)) under timed conditions. Vision drop across environments was calculated, and repeatability of visual scores was determined.
RESULTS: BCVA significantly reduced with decreasing contrast in all eyes. M1 scores for BCVA were greater than M2 and M3 (P
CONCLUSION: The CVA allowed analysis of the visual complaints that AMD patients experience with different lighting/contrast time-dependent conditions. BCVA changed significantly under different lighting/contrast conditions in all eyes, however, AMD eyes were more affected by contrast reduction than normal eyes. In AMD eyes, timed conditions using the CVA led to worse BCVA compared to non-timed ETDRS charts.
| Original language | English |
|---|---|
| Pages (from-to) | 1231-1238 |
| Number of pages | 8 |
| Journal | Eye (London, England) |
| Volume | 28 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 1 2014 |
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ASJC Scopus subject areas
- Medicine(all)
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Visual function assessment in simulated real-life situations in patients with age-related macular degeneration compared to normal subjects. / Barteselli, G.; Gomez, M. L.; Doede, A. L.; Chhablani, J.; Gutstein, W.; Bartsch, D. U.; Dustin, L.; Azen, S. P.; Freeman, W. R.
In: Eye (London, England), Vol. 28, No. 10, 01.10.2014, p. 1231-1238.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Visual function assessment in simulated real-life situations in patients with age-related macular degeneration compared to normal subjects
AU - Barteselli, G.
AU - Gomez, M. L.
AU - Doede, A. L.
AU - Chhablani, J.
AU - Gutstein, W.
AU - Bartsch, D. U.
AU - Dustin, L.
AU - Azen, S. P.
AU - Freeman, W. R.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - PURPOSE: To evaluate visual function variations in eyes with age-related macular degeneration (AMD) compared to normal eyes under different light/contrast conditions using a time-dependent visual acuity testing instrument, the Central Vision Analyzer (CVA).METHODS: Overall, 37 AMD eyes and 35 normal eyes were consecutively tested with the CVA after assessing best-corrected visual acuity (BCVA) using ETDRS charts. The CVA established visual thresholds for three mesopic environments (M1 (high contrast), M2 (medium contrast), and M3 (low contrast)) and three backlight-glare environments (G1 (high contrast, equivalent to ETDRS), G2 (medium contrast), and G3 (low contrast)) under timed conditions. Vision drop across environments was calculated, and repeatability of visual scores was determined.RESULTS: BCVA significantly reduced with decreasing contrast in all eyes. M1 scores for BCVA were greater than M2 and M3 (PCONCLUSION: The CVA allowed analysis of the visual complaints that AMD patients experience with different lighting/contrast time-dependent conditions. BCVA changed significantly under different lighting/contrast conditions in all eyes, however, AMD eyes were more affected by contrast reduction than normal eyes. In AMD eyes, timed conditions using the CVA led to worse BCVA compared to non-timed ETDRS charts.
AB - PURPOSE: To evaluate visual function variations in eyes with age-related macular degeneration (AMD) compared to normal eyes under different light/contrast conditions using a time-dependent visual acuity testing instrument, the Central Vision Analyzer (CVA).METHODS: Overall, 37 AMD eyes and 35 normal eyes were consecutively tested with the CVA after assessing best-corrected visual acuity (BCVA) using ETDRS charts. The CVA established visual thresholds for three mesopic environments (M1 (high contrast), M2 (medium contrast), and M3 (low contrast)) and three backlight-glare environments (G1 (high contrast, equivalent to ETDRS), G2 (medium contrast), and G3 (low contrast)) under timed conditions. Vision drop across environments was calculated, and repeatability of visual scores was determined.RESULTS: BCVA significantly reduced with decreasing contrast in all eyes. M1 scores for BCVA were greater than M2 and M3 (PCONCLUSION: The CVA allowed analysis of the visual complaints that AMD patients experience with different lighting/contrast time-dependent conditions. BCVA changed significantly under different lighting/contrast conditions in all eyes, however, AMD eyes were more affected by contrast reduction than normal eyes. In AMD eyes, timed conditions using the CVA led to worse BCVA compared to non-timed ETDRS charts.
UR - http://www.scopus.com/inward/record.url?scp=84927677652&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84927677652&partnerID=8YFLogxK
U2 - 10.1038/eye.2014.189
DO - 10.1038/eye.2014.189
M3 - Article
C2 - 25081294
AN - SCOPUS:84927677652
VL - 28
SP - 1231
EP - 1238
JO - Eye
JF - Eye
SN - 0950-222X
IS - 10
ER -