Abstract
Aims - To determine if there is any association between the findings of visual assessment performed at the age of 5 months and neurodevelopmental outcome at the age of 2 years in children who have sustained hypoxic- ischaemic insults. Methods - Twenty nine term infants with hypoxic-ischaemic encephalopathy and/or brain lesions on neonatal magnetic resonance imaging (MRI) were prospectively evaluated. At 5 months of age all the infants had their visual function assessed using the Atkinson Battery of Child Development for Examining Functional Vision, which includes the assessments of optokinetic nystagmus (OKN), acuity, visual fields, fixation shift and phase and orientation reversal visual evoked potentials. At 2 years of age the children had a structured neurological evaluation and a Griffiths developmental assessment. Results - There was good correlation between the extent of the early detected visual impairment and both neuromotor and global development. Children with more than three out of five abnormal visual tests at 5 months of age tended to have abnormal neurological examination results and abnormal developmental quotients. Children with three or fewer abnormalities tended to have developmental quotients in the normal range; the level of their performance, however, was still related to the number of visual tests passed. Conclusions - Individual visual tests can provide important prognostic information. While abnormal OKN and acuity were always associated with abnormal outcome, normal results on visual evoked potentials and fixation shift tended to be associated with normal outcome.
| Original language | English |
|---|---|
| Journal | Archives of Disease in Childhood: Fetal and Neonatal Edition |
| Volume | 80 |
| Issue number | 2 |
| Publication status | Published - 1999 |
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Keywords
- Hypoxia-ischaemia
- Neurological outcome
- Visual evoked potentials
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Visual function in term infants with hypoxic-ischaemic insults : Correlation with neurodevelopment at 2 years of age. / Mercuri, Eugenio; Haataja, Leena; Guzzetta, Andrea; Anker, Shirley; Cowan, Frances; Rutherford, Mary; Andrew, Rachel; Braddick, Oliver; Cioni, Giovanni; Dubowitz, Lilly; Atkinson, Janette.
In: Archives of Disease in Childhood: Fetal and Neonatal Edition, Vol. 80, No. 2, 1999.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Visual function in term infants with hypoxic-ischaemic insults
T2 - Correlation with neurodevelopment at 2 years of age
AU - Mercuri, Eugenio
AU - Haataja, Leena
AU - Guzzetta, Andrea
AU - Anker, Shirley
AU - Cowan, Frances
AU - Rutherford, Mary
AU - Andrew, Rachel
AU - Braddick, Oliver
AU - Cioni, Giovanni
AU - Dubowitz, Lilly
AU - Atkinson, Janette
PY - 1999
Y1 - 1999
N2 - Aims - To determine if there is any association between the findings of visual assessment performed at the age of 5 months and neurodevelopmental outcome at the age of 2 years in children who have sustained hypoxic- ischaemic insults. Methods - Twenty nine term infants with hypoxic-ischaemic encephalopathy and/or brain lesions on neonatal magnetic resonance imaging (MRI) were prospectively evaluated. At 5 months of age all the infants had their visual function assessed using the Atkinson Battery of Child Development for Examining Functional Vision, which includes the assessments of optokinetic nystagmus (OKN), acuity, visual fields, fixation shift and phase and orientation reversal visual evoked potentials. At 2 years of age the children had a structured neurological evaluation and a Griffiths developmental assessment. Results - There was good correlation between the extent of the early detected visual impairment and both neuromotor and global development. Children with more than three out of five abnormal visual tests at 5 months of age tended to have abnormal neurological examination results and abnormal developmental quotients. Children with three or fewer abnormalities tended to have developmental quotients in the normal range; the level of their performance, however, was still related to the number of visual tests passed. Conclusions - Individual visual tests can provide important prognostic information. While abnormal OKN and acuity were always associated with abnormal outcome, normal results on visual evoked potentials and fixation shift tended to be associated with normal outcome.
AB - Aims - To determine if there is any association between the findings of visual assessment performed at the age of 5 months and neurodevelopmental outcome at the age of 2 years in children who have sustained hypoxic- ischaemic insults. Methods - Twenty nine term infants with hypoxic-ischaemic encephalopathy and/or brain lesions on neonatal magnetic resonance imaging (MRI) were prospectively evaluated. At 5 months of age all the infants had their visual function assessed using the Atkinson Battery of Child Development for Examining Functional Vision, which includes the assessments of optokinetic nystagmus (OKN), acuity, visual fields, fixation shift and phase and orientation reversal visual evoked potentials. At 2 years of age the children had a structured neurological evaluation and a Griffiths developmental assessment. Results - There was good correlation between the extent of the early detected visual impairment and both neuromotor and global development. Children with more than three out of five abnormal visual tests at 5 months of age tended to have abnormal neurological examination results and abnormal developmental quotients. Children with three or fewer abnormalities tended to have developmental quotients in the normal range; the level of their performance, however, was still related to the number of visual tests passed. Conclusions - Individual visual tests can provide important prognostic information. While abnormal OKN and acuity were always associated with abnormal outcome, normal results on visual evoked potentials and fixation shift tended to be associated with normal outcome.
KW - Hypoxia-ischaemia
KW - Neurological outcome
KW - Visual evoked potentials
UR - http://www.scopus.com/inward/record.url?scp=0032992083&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032992083&partnerID=8YFLogxK
M3 - Article
C2 - 10325784
AN - SCOPUS:0032992083
VL - 80
JO - Archives of Disease in Childhood: Fetal and Neonatal Edition
JF - Archives of Disease in Childhood: Fetal and Neonatal Edition
SN - 1359-2998
IS - 2
ER -