Visual neglect as a disconnection syndrome? A confirmatory case report

Francesca Ciaraffa, Gianmarco Castelli, Eugenio Agostino Parati, Paolo Bartolomeo, Alberto Bizzi

Research output: Contribution to journalArticlepeer-review


Visual neglect has classically been associated with right hemisphere injury in parietal, frontal, or temporal cortex, in the basal ganglia or in the thalamus. More recently, visual neglect has been associated with injury extended into fronto-parietal white matter tracts. However, in most published cases white and gray matter injuries were associated. We present the anatomo-clinical study of a patient presenting with severe acute left visual neglect due to ischemic infarct limited to the right cerebral hemisphere white matter. Magnetic resonance diffusion tensor imaging tractography was instrumental to accurately localize the injury to the right arcuate fasciculus that is a component of the large-scale networks controlling visuo-spatial attention. These results add to a growing appreciation that neglect may result from disruption of a distributed attentional network.

Original languageEnglish
Pages (from-to)351-359
Number of pages9
Issue number4
Publication statusPublished - Aug 2013


  • Arcuate fasciculus
  • Diffusion tensor imaging
  • MR tractography
  • Stroke
  • Visual neglect

ASJC Scopus subject areas

  • Clinical Neurology
  • Arts and Humanities (miscellaneous)


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