Abstract
Vitamin D (vitD) has been shown to have multiple immunomodulatory properties. Hypovitaminosis D has been described in many systemic autoimmune diseases. Antiphospholipid syndrome (APS), an autoimmune disease characterized by immune-mediated thrombosis and pregnancy loss, is a peculiar model for studying vitD, since these patients do not usually have a full-blown autoimmune disease, nor do they have particular restrictions regarding sun exposure. We assessed 25-OH vitD levels in 115 APS and 128 normal healthy donors (NHD) with the LIAISON chemiluminescent immunoassay by DiaSorin (Italy). Median values were lower in APS patients than in NHD, with the greatest difference occurring during summertime (p
Original language | English |
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Pages (from-to) | 736-740 |
Number of pages | 5 |
Journal | Lupus |
Volume | 21 |
Issue number | 7 |
DOIs | |
Publication status | Published - Jun 2012 |
Keywords
- Antinuclear antibodies (ANA)
- antiphospholipid syndrome (APS)
- hypovitaminosis D
- thrombosis
- vitamin D (vitD)
ASJC Scopus subject areas
- Rheumatology