Vitamin D and antiphospholipid syndrome

L. Andreoli; S. Piantoni; F. Dall'Ara; F. Allegri; P. L. Meroni; A. Tincani

doi:10.1177/0961203312446386

Vitamin D and antiphospholipid syndrome

L. Andreoli, S. Piantoni, F. Dall'Ara, F. Allegri, P. L. Meroni, A. Tincani

Fondazione Istituto Auxologico Italiano

Research output: Contribution to journal › Article › peer-review

Abstract

Vitamin D (vitD) has been shown to have multiple immunomodulatory properties. Hypovitaminosis D has been described in many systemic autoimmune diseases. Antiphospholipid syndrome (APS), an autoimmune disease characterized by immune-mediated thrombosis and pregnancy loss, is a peculiar model for studying vitD, since these patients do not usually have a full-blown autoimmune disease, nor do they have particular restrictions regarding sun exposure. We assessed 25-OH vitD levels in 115 APS and 128 normal healthy donors (NHD) with the LIAISON chemiluminescent immunoassay by DiaSorin (Italy). Median values were lower in APS patients than in NHD, with the greatest difference occurring during summertime (p

Original language	English
Pages (from-to)	736-740
Number of pages	5
Journal	Lupus
Volume	21
Issue number	7
DOIs	https://doi.org/10.1177/0961203312446386
Publication status	Published - Jun 2012

Keywords

Antinuclear antibodies (ANA)
antiphospholipid syndrome (APS)
hypovitaminosis D
thrombosis
vitamin D (vitD)

ASJC Scopus subject areas

Rheumatology

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10.1177/0961203312446386

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AU - Piantoni, S.

AU - Dall'Ara, F.

AU - Allegri, F.

AU - Meroni, P. L.

AU - Tincani, A.

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Vitamin D and antiphospholipid syndrome

Abstract

Keywords

ASJC Scopus subject areas

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