Vitamin D and erectile dysfunction

Alessandra Barassi, Raffaele Pezzilli, Giovanni M. Colpi, Massimiliano M. Corsi Romanelli, Gian Vico Melzi d'Eril

Research output: Contribution to journalArticlepeer-review


Introduction: Endothelial dysfunction has been demonstrated to play an important role in pathogenesis of erectile dysfunction (ED) and vitamin D deficiency is deemed to promote endothelial dysfunctions. Aim: To evaluate the status of serum vitamin D in a group of patients with ED. Methods: Diagnosis and severity of ED was based on the IIEF-5 and its aetiology was classified as arteriogenic (A-ED), borderline (BL-ED), and non-arteriogenic (NA-ED) with penile-echo-color-Doppler in basal condition and after intracaversous injection of prostaglandin E1. Serum vitamin D and intact PTH concentrations were measured. Main Outcome Measures: Vitamin D levels of men with A-ED were compared with those of male with BL-ED and NA-ED. Results: Fifty patients were classified as A-ED, 28 as ED-BL and 65 as NA-ED, for a total of 143 cases. Mean vitamin D level was 21.3ng/mL; vitamin D deficiency (20ng/dL (45% vs. 24%; P

Original languageEnglish
Pages (from-to)2792-2800
Number of pages9
JournalJournal of Sexual Medicine
Issue number11
Publication statusPublished - Nov 1 2014


  • Endothelial dysfunctions
  • Erectile dysfunction
  • Vitamin D

ASJC Scopus subject areas

  • Urology
  • Obstetrics and Gynaecology
  • Reproductive Medicine
  • Medicine(all)


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