TY - JOUR
T1 - Vitamin D in childhood and adolescence
T2 - an expert position statement
AU - Saggese, Giuseppe
AU - Vierucci, Francesco
AU - Boot, Annemieke M.
AU - Czech-Kowalska, Justyna
AU - Weber, Giovanna
AU - Camargo, Carlos A.
AU - Mallet, Eric
AU - Fanos, Margherita
AU - Shaw, Nick J.
AU - Holick, Michael F.
PY - 2015/5/1
Y1 - 2015/5/1
N2 - Vitamin D is a key hormone in the regulation of calcium and phosphorus metabolism and plays a pivotal role in bone health, particularly during pediatric age when nutritional rickets and impaired bone mass acquisition may occur. Great interest has been placed in recent years on vitamin D’s extraskeletal actions. However, while recent data suggest a possible role of vitamin D in the pathogenesis of several pathological conditions, including infectious and autoimmune diseases, the actual impact of vitamin D status on the global health of children and adolescents, other than bone, remains a subject of debate. In the meantime, pediatricians still need to evaluate the determinants of vitamin D status and consider vitamin D supplementation in children and adolescents at risk of deficiency. This review is the result of an expert meeting that was held during the congress “Update on vitamin D and bone disease in childhood” convened in Pisa, Italy, in May 2013. Conclusion: The collaboration of the international group of experts produced this “state of the art” review on vitamin D in childhood and adolescence. After dealing with vitamin D status and its determinants, the review outlines the current debate on vitamin D’s health benefits, concluding with a practical approach to vitamin D supplementation during childhood and adolescence.
AB - Vitamin D is a key hormone in the regulation of calcium and phosphorus metabolism and plays a pivotal role in bone health, particularly during pediatric age when nutritional rickets and impaired bone mass acquisition may occur. Great interest has been placed in recent years on vitamin D’s extraskeletal actions. However, while recent data suggest a possible role of vitamin D in the pathogenesis of several pathological conditions, including infectious and autoimmune diseases, the actual impact of vitamin D status on the global health of children and adolescents, other than bone, remains a subject of debate. In the meantime, pediatricians still need to evaluate the determinants of vitamin D status and consider vitamin D supplementation in children and adolescents at risk of deficiency. This review is the result of an expert meeting that was held during the congress “Update on vitamin D and bone disease in childhood” convened in Pisa, Italy, in May 2013. Conclusion: The collaboration of the international group of experts produced this “state of the art” review on vitamin D in childhood and adolescence. After dealing with vitamin D status and its determinants, the review outlines the current debate on vitamin D’s health benefits, concluding with a practical approach to vitamin D supplementation during childhood and adolescence.
KW - 25-Hydroxyvitamin D
KW - Adolescents
KW - Children
KW - Supplementation
KW - Vitamin D
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U2 - 10.1007/s00431-015-2524-6
DO - 10.1007/s00431-015-2524-6
M3 - Article
C2 - 25833762
AN - SCOPUS:84937759847
VL - 174
SP - 565
EP - 576
JO - European Journal of Pediatrics
JF - European Journal of Pediatrics
SN - 0340-6199
IS - 5
ER -