Vitamin D in kidney transplant recipients


Yuri Battaglia, Elena Cojocaru, Fulvio Fiorini, Antonio Granata, Pasquale Esposito, Luigi Russo, Alessandra Bortoluzzi, Alda Storari, Domenico Russo

Research output: Contribution to journalReview articlepeer-review

Abstract

Kidney transplant recipients (KTRs) are susceptible to low levels of vitamin D, which may be responsible for mineral and bone metabolism disorders and play some role in the occurrence of cardiovascular, metabolic, immunologic, neoplastic, and infectious complications after kidney transplant. Kidney Disease Improving Global Outcomes (KDIGO) guidelines of the year 2017 recommended vitamin D supplementation in the first 12 months after transplant using the same treatment strategies for the general population. However, no recommendations are provided after the first 12 months due to a lack of sufficient data. This review analyses some studies that assessed the vitamin D status of KTRs and the effects of nutritional and active vitamin D supplementation on bone mineral density, cardiovascular disease, proteinuria, and graft function in KTRs.

Original languageEnglish
Pages (from-to)57-64
Number of pages8
JournalClinical Nephrology
Volume93
Issue number2
DOIs
Publication statusPublished - Feb 2020

Keywords

  • Bone Density
  • Bone Diseases, Metabolic/prevention & control
  • Cardiovascular Diseases/prevention & control
  • Dietary Supplements
  • Graft Survival/drug effects
  • Humans
  • Kidney Transplantation
  • Proteinuria/prevention & control
  • Vitamin D/administration & dosage
  • Vitamins/administration & dosage

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