Vitamin D in pediatric age: Consensus of the Italian Pediatric Society and the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Federation of Pediatricians

Giuseppe Saggese, Francesco Vierucci, Flavia Prodam, Fabio Cardinale, Irene Cetin, Elena Chiappini, Gian Luigi De Angelis, Maddalena Massari, Emanuele Miraglia Del Giudice, Michele Miraglia Del Giudice, Diego Peroni, Luigi Terracciano, Rino Agostiniani, Domenico Careddu, Daniele Giovanni Ghiglioni, Gianni Bona, Giuseppe Di Mauro, Giovanni Corsello

Research output: Contribution to journalReview article

Abstract

Vitamin D plays a pivotal role in the regulation of calcium-phosphorus metabolism, particularly during pediatric age when nutritional rickets and impaired bone mass acquisition may occur. Besides its historical skeletal functions, in the last years it has been demonstrated that vitamin D directly or indirectly regulates up to 1250 genes, playing so-called extraskeletal actions. Indeed, recent data suggest a possible role of vitamin D in the pathogenesis of several pathological conditions, including infectious, allergic and autoimmune diseases. Thus, vitamin D deficiency may affect not only musculoskeletal health but also a potentially wide range of acute and chronic conditions. At present, the prevalence of vitamin D deficiency is high in Italian children and adolescents, and national recommendations on vitamin D supplementation during pediatric age are lacking. An expert panel of the Italian Society of Preventive and Social Pediatrics reviewed available literature focusing on randomized controlled trials of vitamin D supplementation to provide a practical approach to vitamin D supplementation for infants, children and adolescents.

Original languageEnglish
Article number51
Pages (from-to)1DUMMY
JournalItalian Journal of Pediatrics
Volume44
Issue number1
DOIs
Publication statusPublished - May 8 2018

Keywords

  • Adolescents
  • Children
  • Deficiency
  • Hypovitaminosis D
  • Supplementation
  • Vitamin D

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Fingerprint Dive into the research topics of 'Vitamin D in pediatric age: Consensus of the Italian Pediatric Society and the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Federation of Pediatricians'. Together they form a unique fingerprint.

  • Cite this

    Saggese, G., Vierucci, F., Prodam, F., Cardinale, F., Cetin, I., Chiappini, E., De Angelis, G. L., Massari, M., Miraglia Del Giudice, E., Miraglia Del Giudice, M., Peroni, D., Terracciano, L., Agostiniani, R., Careddu, D., Ghiglioni, D. G., Bona, G., Di Mauro, G., & Corsello, G. (2018). Vitamin D in pediatric age: Consensus of the Italian Pediatric Society and the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Federation of Pediatricians. Italian Journal of Pediatrics, 44(1), 1DUMMY. [51]. https://doi.org/10.1186/s13052-018-0488-7