Vitamin D levels and chronic hepatitis C

Filomena Morisco, Annamaria Colao, Maria Guarino, Vincenzo Lembo, Rocco Granata, Laura Donnarumma, Francesco Auriemma, Anna Mariniello, Giovanna Mazzone, Carolina Di Somma, Manila Rubino, Federica Cariati, Claudia Pivonello, Ilaria Loperto, Nicola Caporaso

Research output: Contribution to journalArticle

Abstract

Background and purpose: Vitamin D (VitD) is involved in homeostasis of calcium and interacts with parathyroid hormone (PTH). Low levels of VitD in chronic liver diseases, in particular in chronic hepatitis C (CHC) was reported. We aimed to determine the levels of VitD and PTH in patients with CHC without cirrhosis to evaluate the disturbance of VitD-PTH axis. Methods: We conduced a case-control study enrolling 59 patients with CHC and 59 controls. We determined serum concentration of VitD, PTH, calcium and phosphate. VitD was quantified by chemiluminescence immunoassay. PTH was measured by 2-site chemiluminescent enzyme-labeled immunoassay. Results: The mean value of VitD was 26.28 and 28.43ng/ml in HCV patients and controls respectively (p

Original languageEnglish
Journale-SPEN Journal
Volume8
Issue number4
DOIs
Publication statusPublished - Aug 2013

Keywords

  • Calcium
  • Chronic hepatitis C
  • Health problem
  • Parathyroid hormone
  • Phosphate
  • Vitamin D deficiency

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

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    Morisco, F., Colao, A., Guarino, M., Lembo, V., Granata, R., Donnarumma, L., Auriemma, F., Mariniello, A., Mazzone, G., Di Somma, C., Rubino, M., Cariati, F., Pivonello, C., Loperto, I., & Caporaso, N. (2013). Vitamin D levels and chronic hepatitis C. e-SPEN Journal, 8(4). https://doi.org/10.1016/j.clnme.2013.04.006