Vitamin K is necessary for the maintenance of normal functional activity of several coagulation factors. Vitamin K defficiency occurs in newborns expecially those who are breast-fed and who do not receive Vitamin K prophylaxis at birth. Later, Vitamin K deficiency may result from malabsorption syndromes, liver disease and the use of antibiotics and anticoagulant drugs. We report a case of late Hemorragic Disease as unusual clinical manifestation of Cystic Fibrosis in a 5 month old infant. Although Vitamin K-deficiency occurs infrequently in Cystic Fibrosis, this diagnostic hypothesis should be considered in patients with Vitamin K-dependent Hemorragic Disease.
|Number of pages||4|
|Journal||Rivista Italiana di Pediatria|
|Publication status||Published - 1995|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health