Vitro methods to investigate the effect of different metals on immune cells

G. Ciapetti, L. Landi, A. Pizzoferrato

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In order to verify possible 'in vitro' metal-cell interactions, different experimental methods have been developed and applied on cells of the immune system. Lymphocytes and granulocytes from human peripheral blood were tested after contact with metal powder in suspension or metal extracts. Lymphocyte transformation test showed that molybdenum, cobalt and nickel can inhibit the proliferation of lymphocytes, even at low concentrations. Granulocyte polarization assay showed that chemokinetic activity of such cells is depending on both the extracted metal and the vehicle of extraction.

Original languageEnglish
Title of host publicationTransactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
PublisherPubl by Soc for Biomaterials
Pages271
Number of pages1
Volume14
Publication statusPublished - 1991
Event17th Annual Meeting of the Society for Biomaterials in conjunction with the 23rd International Biomaterials Symposium - Scottsdale, AZ, USA
Duration: May 1 1991May 5 1991

Other

Other17th Annual Meeting of the Society for Biomaterials in conjunction with the 23rd International Biomaterials Symposium
CityScottsdale, AZ, USA
Period5/1/915/5/91

ASJC Scopus subject areas

  • Materials Science(all)

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  • Cite this

    Ciapetti, G., Landi, L., & Pizzoferrato, A. (1991). Vitro methods to investigate the effect of different metals on immune cells. In Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium (Vol. 14, pp. 271). Publ by Soc for Biomaterials.