Vocal outcome after endoscopic cordectomies for Tis and T1 glottic carcinomas

Giorgio Peretti, Cesare Piazza, Giovanna Cantarella, Cristiano Balzanelli, Piero Nicolai

Research output: Contribution to journalArticle


A cohort of 101 patients with previously untreated glottic cancer (15 Tis, 66 T1a, and 20 T1b) who underwent endoscopic CO2 laser excision between January 1995 and December 1997 was prospectively analyzed. The depth and extension of the excision were graded according to the European Laryngological Society Classification including 5 types of cordectomy. All patients were subsequently examined every 2 months for a period ranging from 30 to 66 months (mean, 48 months). The rates of 5-year overall survival, disease-free survival, ultimate local control with laser alone, and laryngeal preservation were 85%, 87%, 93%, and 95%, respectively. Sixty-nine patients underwent, at least 1 year after surgery, videolaryngostroboscopy combined with perceptual and objective evaluation of the voice, and spirometry. Acoustic parameters were compared with those obtained in a matched control group by Kruskal-Wallis test. No statistically significant difference was found (p >.05) between patients submitted to subepithelial (type I) and subligamental (type II) cordectomies and controls.

Original languageEnglish
Pages (from-to)174-179
Number of pages6
JournalAnnals of Otology, Rhinology and Laryngology
Issue number2
Publication statusPublished - Feb 1 2003


  • Carbon dioxide laser
  • Endoscopic cordectomy
  • Glottic cancer
  • Oncological results
  • Vocal outcome

ASJC Scopus subject areas

  • Otorhinolaryngology

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