Volitional regulation of the supplementary motor area with fMRI-BCI neurofeedback in Parkinson's disease: A pilot study

Korhan Buyukturkoglu, Mohit Rana, Sergio Ruiz, Steven A. Hackley, Surjo R. Soekadar, Niels Birbaumer, Ranganatha Sitaram

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

It is hypothesized that a dysfunction of the supplementary motor area (SMA), secondary to a deficit of the nigrostriatal dopamine system, partially contributes to the symptomatology of Parkinson's disease (PD), i.e., akinesia. In this pilot study we investigated the effect of real-time fMRI neurofeedback based volitional up-regulation of the SMA on hand motor performance of one PD patient and 3 healthy volunteers. The effect of learned self-regulation was evaluated with speeded, bimanual, sequenced button-pressing trials, assessed immediately after each baseline and up-regulation block. Our pilot results indicate that volitional up-regulation of SMA is accompanied by slowing of sequenced button presses.

Original languageEnglish
Title of host publicationInternational IEEE/EMBS Conference on Neural Engineering, NER
Pages677-681
Number of pages5
DOIs
Publication statusPublished - 2013
Event2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013 - San Diego, CA, United States
Duration: Nov 6 2013Nov 8 2013

Other

Other2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013
CountryUnited States
CitySan Diego, CA
Period11/6/1311/8/13

ASJC Scopus subject areas

  • Artificial Intelligence
  • Mechanical Engineering

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