Volumetric change of selected organs at risk during IMRT for oropharyngeal cancer

Francesco Ricchetti, Binbin Wu, Todd McNutt, John Wong, Arlene Forastiere, Shanthi Marur, Heather Starmer, Giuseppe Sanguineti

Research output: Contribution to journalArticle

Abstract

Purpose: To assess volumetric changes of selected organs at risk (OAR) during intensity-modulated radiotherapy (IMRT) for oropharyngeal carcinoma. Materials and Methods: Twenty-six consecutive patients that were treated with definitive IMRT ± chemotherapy between November 2007 and November 2008 were selected for the present study. As part of an internal quality assurances program, a repeat kilovolt (KV) computed tomography was planned weekly during the 7-week treatment course. On each available scan, a single observer contoured the parotid submandibular, and thyroid glands (PG/SMG/TG), larynx (L), and constrictor, masticatory, and sternocleidomastoid muscles (CM/MM/SCM) as appropriate. The volume at each scan was compared with the one at planning CT in a pair-wise fashion. p values

Original languageEnglish
Pages (from-to)161-168
Number of pages8
JournalInternational Journal of Radiation Oncology Biology Physics
Volume80
Issue number1
DOIs
Publication statusPublished - May 1 2011

Keywords

  • IMRT
  • Oropharyngeal cancer
  • Volumetric change

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Radiation
  • Cancer Research

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