Voluptuary Habits and Risk of Frontotemporal Dementia: A Case Control Retrospective Study

Lucio Tremolizzo, Elisa Bianchi, Emanuela Susani, Elisabetta Pupillo, Paolo Messina, Angelo Aliprandi, Andrea Salmaggi, Maura Cosseddu, Andrea Pilotto, Barbara Borroni, Alessandro Padovani, Cristina Bonomini, Orazio Zanetti, Ildebrando Appollonio, Ettore Beghi, Carlo Ferrarese

Research output: Contribution to journalArticlepeer-review


Alcohol, coffee, and tobacco consumption was assessed on 151 FTD outpatients and 151 matched controls in a multicenter retrospective case-control design. No association was found for smoking and coffee intake. The risk of FTD was decreased by alcohol consumption (adj. OR 0.30, 95 CI 0.14-0.63); risk reduction was significant in current alcohol consumers (adj. OR 0.22, 95 CI 0.10-0.51). The risk of FTD inversely correlated with the duration of exposure (adj. OR 0.88, 95 CI 0.81-0.95, for every 5 years of exposure increase). Retrospective information and the unknown amount of consumed alcohol are limits of the present work.

Original languageEnglish
Pages (from-to)335-340
Number of pages6
JournalJournal of Alzheimer's Disease
Issue number2
Publication statusPublished - Jan 1 2017


  • Alcohol
  • coffee
  • frontotemporal dementia
  • risk factor
  • smoking
  • voluptuary habits

ASJC Scopus subject areas

  • Clinical Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health


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