VRG: A database of vascular dysfunctions related genes

Sara Zanivan; Davide Corà; Michele Caselle; Federico Bussolino

doi:10.1016/j.camwa.2006.12.097

VRG: A database of vascular dysfunctions related genes

Sara Zanivan, Davide Corà, Michele Caselle, Federico Bussolino

Istituto Oncologico Candiolo

Research output: Contribution to journal › Article › peer-review

Abstract

Heart and vascular defects occur in a large number of hereditary and sporadic human diseases as a result of a complex interplay of genetic factors. Since genome sequencing of many organisms disclosed similarities among genomes, animal models are crucial for the discovery of genes involved in those pathological processes. Therefore we propose a VRG database, in which human data have been manually managed and integrated with mouse information in order to create a catalogue of genes involved in vascular diseases.

Original language	English
Pages (from-to)	1068-1073
Number of pages	6
Journal	Computers and Mathematics with Applications
Volume	55
Issue number	5
DOIs	https://doi.org/10.1016/j.camwa.2006.12.097
Publication status	Published - Mar 2008

Keywords

Animal models
Database
Genome
Human vascular diseases

ASJC Scopus subject areas

Applied Mathematics
Computational Mathematics
Modelling and Simulation

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10.1016/j.camwa.2006.12.097

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abstract = "Heart and vascular defects occur in a large number of hereditary and sporadic human diseases as a result of a complex interplay of genetic factors. Since genome sequencing of many organisms disclosed similarities among genomes, animal models are crucial for the discovery of genes involved in those pathological processes. Therefore we propose a VRG database, in which human data have been manually managed and integrated with mouse information in order to create a catalogue of genes involved in vascular diseases.",

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AU - Corà, Davide

AU - Caselle, Michele

AU - Bussolino, Federico

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AB - Heart and vascular defects occur in a large number of hereditary and sporadic human diseases as a result of a complex interplay of genetic factors. Since genome sequencing of many organisms disclosed similarities among genomes, animal models are crucial for the discovery of genes involved in those pathological processes. Therefore we propose a VRG database, in which human data have been manually managed and integrated with mouse information in order to create a catalogue of genes involved in vascular diseases.

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KW - Genome

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VRG: A database of vascular dysfunctions related genes

Abstract

Keywords

ASJC Scopus subject areas

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