Abstract
Heart and vascular defects occur in a large number of hereditary and sporadic human diseases as a result of a complex interplay of genetic factors. Since genome sequencing of many organisms disclosed similarities among genomes, animal models are crucial for the discovery of genes involved in those pathological processes. Therefore we propose a VRG database, in which human data have been manually managed and integrated with mouse information in order to create a catalogue of genes involved in vascular diseases.
| Original language | English |
|---|---|
| Pages (from-to) | 1068-1073 |
| Number of pages | 6 |
| Journal | Computers and Mathematics with Applications |
| Volume | 55 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Mar 2008 |
Keywords
- Animal models
- Database
- Genome
- Human vascular diseases
ASJC Scopus subject areas
- Applied Mathematics
- Computational Mathematics
- Modelling and Simulation
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Zanivan, S., Corà, D., Caselle, M., & Bussolino, F. (2008). VRG: A database of vascular dysfunctions related genes. Computers and Mathematics with Applications, 55(5), 1068-1073. https://doi.org/10.1016/j.camwa.2006.12.097