Vulnerability to 35% CO2 of panic disorder patients with a history of respiratory disorders

Nicole Van Beek, Giampaolo Perna, Koen Schruers, Kees Verburg, Michele Cucchi, Laura Bellodi, Eric Griez

Research output: Contribution to journalArticlepeer-review

Abstract

Patients with panic disorder often report a history of respiratory pathology. Furthermore, panic disorder patients are vulnerable to CO 2 challenges. The increased CO2 vulnerability displayed by panic disorder patients may be related to lifetime respiratory pathology. We examined whether panic disorder patients with a history of respiratory disorders are more vulnerable to a 35% CO2 challenge than those without such a history. Ninety-six patients with panic disorder were interviewed about their lifetime respiratory status (asthma, bronchitis and various other respiratory conditions) and underwent the challenge. Immediately before and after the CO2 inhalation, the patients filled out the Visual Analogue Scale for Anxiety (VAS-A) and the Panic Symptom List (PSL). We found no differences between the two panic disorder groups on anxiety (VAS-A), panic symptoms (PSL) or panic attacks after the CO2 challenge. Our results suggest that having a PD is an important factor in CO2 vulnerability independent of a history of respiratory disorders.

Original languageEnglish
Pages (from-to)125-130
Number of pages6
JournalPsychiatry Research
Volume120
Issue number2
DOIs
Publication statusPublished - Sep 30 2003

Keywords

  • Asthma
  • Bronchitis
  • Respiratory condition

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Psychology(all)

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