Waldenström’s Macroglobulinemia

Steven P. Treon, Giampaolo Merlini, Meletios A. Dimopoulos

Research output: Chapter in Book/Report/Conference proceedingChapter


Waldenström’s macroglobulinemia (WM) is a lymphoid neoplasm resulting from the accumulation, predominantly in the marrow, of a clonal population of lymphocytes, lymphoplasmacytic cells, and plasma cells, which secrete a monoclonal immunoglobulin (Ig) M (Owen et al., Semin Oncol 30:110, 2003). WM corresponds to lymphoplasmacytic lymphoma (LPL) as defined in the Revised European-American Lymphoma (REAL) and World Health Organization classification systems (Harris et al., Blood 84:1361, 1994; Harris et al., Ann Oncol 10:1419, 1999). Most cases of LPL are WM; less than 5% of cases are IgA-secreting, IgG-secreting, or nonsecreting LPL.

Original languageEnglish
Title of host publicationHematologic Malignancies
PublisherSpringer Verlag
Number of pages30
Publication statusPublished - Jan 1 2018

Publication series

NameHematologic Malignancies
ISSN (Print)2197-9766
ISSN (Electronic)2197-9774


  • Biology
  • Ibrutinib
  • Rituximab
  • Treatment
  • Waldenstrom’s macroglobulinemia

ASJC Scopus subject areas

  • Hematology
  • Oncology


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