Waldenström’s Macroglobulinemia

Steven P. Treon, Giampaolo Merlini, Meletios A. Dimopoulos

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Waldenström’s macroglobulinemia (WM) is a lymphoid neoplasm resulting from the accumulation, predominantly in the marrow, of a clonal population of lymphocytes, lymphoplasmacytic cells, and plasma cells, which secrete a monoclonal immunoglobulin (Ig) M (Owen et al., Semin Oncol 30:110, 2003). WM corresponds to lymphoplasmacytic lymphoma (LPL) as defined in the Revised European-American Lymphoma (REAL) and World Health Organization classification systems (Harris et al., Blood 84:1361, 1994; Harris et al., Ann Oncol 10:1419, 1999). Most cases of LPL are WM; less than 5% of cases are IgA-secreting, IgG-secreting, or nonsecreting LPL.

Original languageEnglish
Title of host publicationHematologic Malignancies
PublisherSpringer Verlag
Pages191-220
Number of pages30
Edition9783319255842
DOIs
Publication statusPublished - Jan 1 2018

Publication series

NameHematologic Malignancies
Number9783319255842
ISSN (Print)2197-9766
ISSN (Electronic)2197-9774

Keywords

  • Biology
  • Ibrutinib
  • Rituximab
  • Treatment
  • Waldenstrom’s macroglobulinemia

ASJC Scopus subject areas

  • Hematology
  • Oncology

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  • Cite this

    Treon, S. P., Merlini, G., & Dimopoulos, M. A. (2018). Waldenström’s Macroglobulinemia. In Hematologic Malignancies (9783319255842 ed., pp. 191-220). (Hematologic Malignancies; No. 9783319255842). Springer Verlag. https://doi.org/10.1007/978-3-319-25586-6_11