Waldenstrom's macrogloblinemia/ lymphoplasmacytic lymphoma

Steven P. Treon, Evdoxia Hatjiharissi, Giampaolo Merlini

Research output: Chapter in Book/Report/Conference proceedingChapter


Waldenström's macroglobulinemia (WM) is a distinct clinicopathological entity resulting from the accumulation, predominantly in the bone marrow, of clonally related lymphocytes, lymphoplasmacytic cells, and plasma cells that secrete a monoclonal IgM protein (Figure 9.1) (1). This condition is considered to correspond to the lymphoplasmacytic lymphoma (LPL) as defined by the Revised European American Lymphoma (REAL) and World Health Organization (WHO) classification systems (2, 3). Most cases of LPL are WM, with less than 5% of cases made up of IgA, IgG, and nonsecreting LPL.

Original languageEnglish
Title of host publicationRare Hematological Malignancies
PublisherSpringer US
Number of pages32
ISBN (Print)9780387737430
Publication statusPublished - 2008

ASJC Scopus subject areas

  • Medicine(all)


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