TY - JOUR
T1 - Warding off recurrent yeast and bacterial vaginal infections
T2 - Lactoferrin and lactobacilli
AU - Superti, Fabiana
AU - De Seta, Francesco
N1 - Publisher Copyright:
© 2020 by the authors. Licensee MDPI, Basel, Switzerland.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/1
Y1 - 2020/1
N2 - Vaginal infections are the most prevalent women’s health problem. Incompetent diagnosis, inappropriate treatments, and antibiotic resistance are the main causes of the unsatisfactory results of conventional, antimicrobic treatment for these infections. Research has thus been conducted to identify new treatments for these genital diseases. The significant enhancement in our knowledge of vaginal microbiota has permitted the development of new, nonpharmacological strategies for the treatment of vaginal infections that seek to restore the balance of vaginal microflora, as opposed to modifying its components. Among these approaches, bioactive compounds, such as probiotics and nutraceutical proteins (such as lactoferrin), deserve particular attention. The aim of this review is to examine the role of probiotics (mainly Lactobacillus spp.) and lactoferrin as new strategies for counteracting bacterial and fungal vaginal infections.
AB - Vaginal infections are the most prevalent women’s health problem. Incompetent diagnosis, inappropriate treatments, and antibiotic resistance are the main causes of the unsatisfactory results of conventional, antimicrobic treatment for these infections. Research has thus been conducted to identify new treatments for these genital diseases. The significant enhancement in our knowledge of vaginal microbiota has permitted the development of new, nonpharmacological strategies for the treatment of vaginal infections that seek to restore the balance of vaginal microflora, as opposed to modifying its components. Among these approaches, bioactive compounds, such as probiotics and nutraceutical proteins (such as lactoferrin), deserve particular attention. The aim of this review is to examine the role of probiotics (mainly Lactobacillus spp.) and lactoferrin as new strategies for counteracting bacterial and fungal vaginal infections.
KW - Aerobic vaginitis
KW - Bacterial vaginosis
KW - Lactobacillus
KW - Lactoferrin
KW - Safety
KW - Vulvovaginal candidiasis
UR - http://www.scopus.com/inward/record.url?scp=85079073855&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85079073855&partnerID=8YFLogxK
U2 - 10.3390/microorganisms8010130
DO - 10.3390/microorganisms8010130
M3 - Review article
AN - SCOPUS:85079073855
VL - 8
JO - Microorganisms
JF - Microorganisms
SN - 2076-2607
IS - 1
M1 - 130
ER -