Weaning from mechanical ventilation: A cross-sectional study of reference values and the discriminative validity of aging

Camilo Corbellini, Cristiane Brenner Eilert Trevisan, Jorge Hugo Villafañe, Alexandre Doval da Costa, Silvia Regina Rios Vieira

Research output: Contribution to journalArticlepeer-review

Abstract

[Purpose] To evaluate pre-extubation variables and check the discriminative validity of age as well as its correlation with weaning failure in elderly patients. [Subjects and Methods] Two hundred thirty-nine consecutive patients (48% female) who were on mechanical ventilation and had undergone orotracheal intubation were divided into four subgroups according to their age: 80 years old. The expiratory volume (VE), respiratory frequency (f), tidal volume (VT), and respiratory frequency/tidal volume ratio (f/VT) were used to examine differences in weaning parameters between the four subgroups, and age was correlated with weaning failure. [Results] The rate of weaning failure was 27.8% in patients aged >80 years and 22.1% in patients aged T and f values and lower VT values. The areas under the receiver operating characteristic curves for f/VT ratio were smaller than those published previously. [Conclusion] Our results indicate that aging influences weaning criteria without causing an increase in weaning failure.

Original languageEnglish
Pages (from-to)1945-1950
Number of pages6
JournalJournal of Physical Therapy Science
Volume27
Issue number6
Publication statusPublished - Jun 30 2015

Keywords

  • Aging
  • Mechanical ventilation
  • Weaning

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation

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