Wegener's granulomatosis confined to nervous system.

M. Lucchetta, M. Favero, F. Schiavon, A. Cagnin, R. Manara, A. Rotilio, E. Orvieto, C. Giannini, C. Briani

Research output: Contribution to journalArticle

Abstract

Wegener's granulomatosis (WG) is a multisystemic necrotising granulomatous vasculitis of small and medium sized vessels, that primarily involves the upper and lower respiratory tracts, lung tissues and kidneys. Serum antineutrophil cytoplasmic antibodies (ANCA) are a sensitive and specific marker of WG. Whereas the peripheral nervous system is often involved in WG, central nervous system manifestations are reported only in 2-8%, and are rarely present at onset. We report on a patient with atypical neurological presentation of ANCA negative WG in whom the diagnosis was made only after a meningeal biopsy.

Original languageEnglish
JournalBMJ Case Reports
Volume2008
Publication statusPublished - 2008

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Granulomatosis with Polyangiitis
Nervous System
Antineutrophil Cytoplasmic Antibodies
Peripheral Nervous System
Vasculitis
Respiratory System
Central Nervous System
Kidney
Biopsy
Lung
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lucchetta, M., Favero, M., Schiavon, F., Cagnin, A., Manara, R., Rotilio, A., ... Briani, C. (2008). Wegener's granulomatosis confined to nervous system. BMJ Case Reports, 2008.

Wegener's granulomatosis confined to nervous system. / Lucchetta, M.; Favero, M.; Schiavon, F.; Cagnin, A.; Manara, R.; Rotilio, A.; Orvieto, E.; Giannini, C.; Briani, C.

In: BMJ Case Reports, Vol. 2008, 2008.

Research output: Contribution to journalArticle

Lucchetta, M, Favero, M, Schiavon, F, Cagnin, A, Manara, R, Rotilio, A, Orvieto, E, Giannini, C & Briani, C 2008, 'Wegener's granulomatosis confined to nervous system.', BMJ Case Reports, vol. 2008.
Lucchetta M, Favero M, Schiavon F, Cagnin A, Manara R, Rotilio A et al. Wegener's granulomatosis confined to nervous system. BMJ Case Reports. 2008;2008.
Lucchetta, M. ; Favero, M. ; Schiavon, F. ; Cagnin, A. ; Manara, R. ; Rotilio, A. ; Orvieto, E. ; Giannini, C. ; Briani, C. / Wegener's granulomatosis confined to nervous system. In: BMJ Case Reports. 2008 ; Vol. 2008.
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AU - Orvieto, E.

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