Wegener's granulomatosis confined to nervous system.

M. Lucchetta, M. Favero, F. Schiavon, A. Cagnin, R. Manara, A. Rotilio, E. Orvieto, C. Giannini, C. Briani

Research output: Contribution to journalArticlepeer-review

Abstract

Wegener's granulomatosis (WG) is a multisystemic necrotising granulomatous vasculitis of small and medium sized vessels, that primarily involves the upper and lower respiratory tracts, lung tissues and kidneys. Serum antineutrophil cytoplasmic antibodies (ANCA) are a sensitive and specific marker of WG. Whereas the peripheral nervous system is often involved in WG, central nervous system manifestations are reported only in 2-8%, and are rarely present at onset. We report on a patient with atypical neurological presentation of ANCA negative WG in whom the diagnosis was made only after a meningeal biopsy.

Original languageEnglish
JournalBMJ Case Reports
Volume2008
Publication statusPublished - 2008

ASJC Scopus subject areas

  • Medicine(all)

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