Wegener's granulomatosis confined to nervous system

M. Lucchetta, M. Favero, F. Schiavon, A. Cagnin, R. Manara, A. Rotilio, E. Orvieto, C. Giannini, C. Briani

Research output: Contribution to journalArticle

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Abstract

Wegener's granulomatosis (WG) is a multisy stemic necrotising granulomatous vasculitis of small and medium sized vessels, that primarily involves the upper and lower respiratory tracts, lung tissues and kidneys. Serum antineutrophil cytoplasmic antibodies (ANCA) are a sensitive and specific marker of WG. Whereas the peripheral nervous system is often involved in WG, central nervous system manifestations are reported only in 2-8%, and are rarely present at onset. We report on a patient with atypical neurological presentation of ANCA negative WG in whom the diagnosis was made only after a meningeal biopsy.

Original languageEnglish
JournalBMJ Case Reports
DOIs
Publication statusPublished - Nov 20 2008

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Granulomatosis with Polyangiitis
Nervous System
Antineutrophil Cytoplasmic Antibodies
Peripheral Nervous System
Vasculitis
Respiratory System
Central Nervous System
Kidney
Biopsy
Lung
Serum

ASJC Scopus subject areas

  • Medicine(all)

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Lucchetta, M., Favero, M., Schiavon, F., Cagnin, A., Manara, R., Rotilio, A., ... Briani, C. (2008). Wegener's granulomatosis confined to nervous system. BMJ Case Reports. https://doi.org/10.1136/bcr.06.2008.0283

Wegener's granulomatosis confined to nervous system. / Lucchetta, M.; Favero, M.; Schiavon, F.; Cagnin, A.; Manara, R.; Rotilio, A.; Orvieto, E.; Giannini, C.; Briani, C.

In: BMJ Case Reports, 20.11.2008.

Research output: Contribution to journalArticle

Lucchetta, M, Favero, M, Schiavon, F, Cagnin, A, Manara, R, Rotilio, A, Orvieto, E, Giannini, C & Briani, C 2008, 'Wegener's granulomatosis confined to nervous system', BMJ Case Reports. https://doi.org/10.1136/bcr.06.2008.0283
Lucchetta M, Favero M, Schiavon F, Cagnin A, Manara R, Rotilio A et al. Wegener's granulomatosis confined to nervous system. BMJ Case Reports. 2008 Nov 20. https://doi.org/10.1136/bcr.06.2008.0283
Lucchetta, M. ; Favero, M. ; Schiavon, F. ; Cagnin, A. ; Manara, R. ; Rotilio, A. ; Orvieto, E. ; Giannini, C. ; Briani, C. / Wegener's granulomatosis confined to nervous system. In: BMJ Case Reports. 2008.
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