Wegener's granulomatosis presenting with life-threatening lung hemorrhage in a 7-year-old child

Susanna Esposito, Fabrizia Corona, Annacarla Defilippi, Antonella Petaccia, Giovanna Chidini, Laura Dell'Era, Jelena Bojanin, Edoardo Calderini, Nicola Principi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Wegener's granulomatosis (WG) is an idiopathic systemic disease that usually onsets in adolescence and is rare in young children. Its diagnosis is usually based on the presence of fever with arthralgia and weight loss, associated with symptoms of upper and/or lower respiratory tract involvement and renal disorders. We describe the appearance of a life-threatening lung hemorrhage in the absence of hemoptysis in a 7-year-old girl with a completely negative previous clinical history, who was subsequently diagnosed as having WG. The teaching message is that immediate bronchoscopy with bronchoalveolar lavage seems to be advisable in the presence of severe respiratory distress and bilateral lung as well as renal involvement. When a diffuse alveolar hemorrhage syndrome is demonstrated, WG should be considered among the main etiologies even in a relatively young child without a clinically suggestive history.

Original languageEnglish
Pages (from-to)1665-1668
Number of pages4
JournalRheumatology International
Volume30
Issue number12
DOIs
Publication statusPublished - Nov 2010

Fingerprint

Granulomatosis with Polyangiitis
Hemorrhage
Lung
Kidney
Hemoptysis
Arthralgia
Bronchoscopy
Bronchoalveolar Lavage
Respiratory System
Weight Loss
Teaching
Fever
History

Keywords

  • Crescentic glomerulonephritis
  • Lung hemorrhage
  • Severe respiratory distress
  • Wegener's granulomatosis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

Cite this

Wegener's granulomatosis presenting with life-threatening lung hemorrhage in a 7-year-old child. / Esposito, Susanna; Corona, Fabrizia; Defilippi, Annacarla; Petaccia, Antonella; Chidini, Giovanna; Dell'Era, Laura; Bojanin, Jelena; Calderini, Edoardo; Principi, Nicola.

In: Rheumatology International, Vol. 30, No. 12, 11.2010, p. 1665-1668.

Research output: Contribution to journalArticle

Esposito, Susanna ; Corona, Fabrizia ; Defilippi, Annacarla ; Petaccia, Antonella ; Chidini, Giovanna ; Dell'Era, Laura ; Bojanin, Jelena ; Calderini, Edoardo ; Principi, Nicola. / Wegener's granulomatosis presenting with life-threatening lung hemorrhage in a 7-year-old child. In: Rheumatology International. 2010 ; Vol. 30, No. 12. pp. 1665-1668.
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AU - Chidini, Giovanna

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