Werner's syndrome: Seven cases in one family

G. Rabbiosi, G. Borroni

Research output: Contribution to journalArticle

Abstract

7 cases of Werner's syndrome in one family of northern Sardinia (the female:male ratio being 4:3) are reported. A 9-yr-old girl affected with Cooley's anemia is reported too. The typical complete pattern of the syndrome was observed in patients in the fourth devade of their lives, whereas in the 2 youngest ones, some features were missing, 1 patient died of gastric carcinoma, 1 of cachexia. Consanguinity was established in two generations. The genealogical tree suggests an autosomal recessive mode of inheritance. Genealogical, clinical, biochemical, and histopathological studies were performed. As far as we know, this is the largest number of patients with Werner's syndrome reported in one family.

Original languageEnglish
Pages (from-to)355-360
Number of pages6
JournalDermatologica
Volume158
Issue number5
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Dermatology

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    Rabbiosi, G., & Borroni, G. (1979). Werner's syndrome: Seven cases in one family. Dermatologica, 158(5), 355-360.