What Is the Best Initial Empirical Treatment of Suspected Sepsis in a Newborn Readmitted Soon after Discharge Home in an Era of Increased Resistance to Antibiotics? A Report of Two Cases

Elio Castagnola, Livia Gargiullo, Salvatore Renna, Anna Loy, Francesco Risso, Andrea Moscatelli, Ivana Baldelli, Giuliana Cangemi, Roberto Bandettini

Research output: Contribution to journalArticlepeer-review

Abstract

Background Colonization/infection by antibiotic-resistant bacteria is becoming a major threat to health care systems. Case report Two septic neonates were readmitted in our hospital few days after hospital discharge. In both of them, microbiological workup revealed an infection caused by multiresistant pathogens. Noteworthy, one baby had received intensive care management for 4 weeks, whereas the other had been vaginally delivered and sent home on his second day of life. Conclusion These cases suggest that in countries and/or hospital with high prevalence of colonization/infection by resistant pathogens in nurseries, neonatal intensive care units, and obstetric wards, the choice of initial therapy of suspected sepsis in a neonate readmitted from home soon after discharge should take into account the possibility of an infection due to a multiresistant pathogen.

Original languageEnglish
Pages (from-to)1090-1092
Number of pages3
JournalAmerican Journal of Perinatology
Volume33
Issue number11
DOIs
Publication statusPublished - Sep 1 2016

Keywords

  • antibiotic-resistant pathogen
  • initial empirical treatment
  • neonate
  • suspected sepsis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

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