Abstract
Background Colonization/infection by antibiotic-resistant bacteria is becoming a major threat to health care systems. Case report Two septic neonates were readmitted in our hospital few days after hospital discharge. In both of them, microbiological workup revealed an infection caused by multiresistant pathogens. Noteworthy, one baby had received intensive care management for 4 weeks, whereas the other had been vaginally delivered and sent home on his second day of life. Conclusion These cases suggest that in countries and/or hospital with high prevalence of colonization/infection by resistant pathogens in nurseries, neonatal intensive care units, and obstetric wards, the choice of initial therapy of suspected sepsis in a neonate readmitted from home soon after discharge should take into account the possibility of an infection due to a multiresistant pathogen.
| Original language | English |
|---|---|
| Pages (from-to) | 1090-1092 |
| Number of pages | 3 |
| Journal | American Journal of Perinatology |
| Volume | 33 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - Sep 1 2016 |
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Keywords
- antibiotic-resistant pathogen
- initial empirical treatment
- neonate
- suspected sepsis
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Obstetrics and Gynaecology
Cite this
What Is the Best Initial Empirical Treatment of Suspected Sepsis in a Newborn Readmitted Soon after Discharge Home in an Era of Increased Resistance to Antibiotics? A Report of Two Cases. / Castagnola, Elio; Gargiullo, Livia; Renna, Salvatore; Loy, Anna; Risso, Francesco; Moscatelli, Andrea; Baldelli, Ivana; Cangemi, Giuliana; Bandettini, Roberto.
In: American Journal of Perinatology, Vol. 33, No. 11, 01.09.2016, p. 1090-1092.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - What Is the Best Initial Empirical Treatment of Suspected Sepsis in a Newborn Readmitted Soon after Discharge Home in an Era of Increased Resistance to Antibiotics? A Report of Two Cases
AU - Castagnola, Elio
AU - Gargiullo, Livia
AU - Renna, Salvatore
AU - Loy, Anna
AU - Risso, Francesco
AU - Moscatelli, Andrea
AU - Baldelli, Ivana
AU - Cangemi, Giuliana
AU - Bandettini, Roberto
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Background Colonization/infection by antibiotic-resistant bacteria is becoming a major threat to health care systems. Case report Two septic neonates were readmitted in our hospital few days after hospital discharge. In both of them, microbiological workup revealed an infection caused by multiresistant pathogens. Noteworthy, one baby had received intensive care management for 4 weeks, whereas the other had been vaginally delivered and sent home on his second day of life. Conclusion These cases suggest that in countries and/or hospital with high prevalence of colonization/infection by resistant pathogens in nurseries, neonatal intensive care units, and obstetric wards, the choice of initial therapy of suspected sepsis in a neonate readmitted from home soon after discharge should take into account the possibility of an infection due to a multiresistant pathogen.
AB - Background Colonization/infection by antibiotic-resistant bacteria is becoming a major threat to health care systems. Case report Two septic neonates were readmitted in our hospital few days after hospital discharge. In both of them, microbiological workup revealed an infection caused by multiresistant pathogens. Noteworthy, one baby had received intensive care management for 4 weeks, whereas the other had been vaginally delivered and sent home on his second day of life. Conclusion These cases suggest that in countries and/or hospital with high prevalence of colonization/infection by resistant pathogens in nurseries, neonatal intensive care units, and obstetric wards, the choice of initial therapy of suspected sepsis in a neonate readmitted from home soon after discharge should take into account the possibility of an infection due to a multiresistant pathogen.
KW - antibiotic-resistant pathogen
KW - initial empirical treatment
KW - neonate
KW - suspected sepsis
UR - http://www.scopus.com/inward/record.url?scp=84986538253&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84986538253&partnerID=8YFLogxK
U2 - 10.1055/s-0036-1586104
DO - 10.1055/s-0036-1586104
M3 - Article
AN - SCOPUS:84986538253
VL - 33
SP - 1090
EP - 1092
JO - American Journal of Perinatology
JF - American Journal of Perinatology
SN - 0735-1631
IS - 11
ER -