Sensibilità della mammografia e della RM a contrasto dinamico per le lesioni neoplastiche non invasive della mammella: Confronto con reference standard istologico dell'intera mammella

Translated title of the contribution: What is the sensitivity of mammography and dynamic MR imaging for DCIS if the whole-breast histopathology is used as a reference standard?

F. Sardanelli, L. Bacigalupo, L. Carbonaro, A. Esseridou, G. M. Giuseppetti, P. Panizza, V. Lattanzio, A. Del Maschio

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose. Our purpose was to compare mammography and dynamic contrast-enhanced magnetic resonance imaging (MRI) in the detection of ductal carcinoma in situ (DCIS). Materials and methods. Ninety patients (aged 58.6±16.1 years) who were candidates for unilateral (n=81) or bilateral (n=9) mastectomy underwent mammography and dynamic contrast-enhanced breast MRI using a coronal three-dimensional gradient-echo sequence with slice thickness ≤3 mm before and after intravenous injection of gadoteridol (0.1 mmol/kg). Mammographic and MR images were evaluated by two offsite readers working in consensus. Pathological examination performed on 5-mm sections covering the whole breast was used as a reference standard. Results. Out of 99 breasts, pathology revealed 26 DCIS in 14 breasts of 14 patients, aged 52.0±9.6 years. Lesion diameter at pathology was

Translated title of the contributionWhat is the sensitivity of mammography and dynamic MR imaging for DCIS if the whole-breast histopathology is used as a reference standard?
Original languageItalian
Pages (from-to)439-451
Number of pages13
JournalRadiologia Medica
Volume113
Issue number3
DOIs
Publication statusPublished - Apr 2008

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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