Abstract
BACKGROUND: Color-Doppler ecocardiography and cardiopulmonary stress test are pivotal in the evaluation of patients with heart failure. Besides determining systolic function through left ventricular ejection fraction (EF), color-Doppler ecocardiography evaluates the presence and degree of functional mitral regurgitation and the severity of diastolic dysfunction. Moreover, in addition to the aerobic capacity indicated by peak O2 consumption, other parameters of cardiopulmonary stress have proven useful for diagnostic purposes, such as the peak VE/VCO2 ratio or ventilatory efficiency. Since in elderly patients with heart failure the functional impairment often is a combination of the effects of aging with those of disease, the relationship between symptoms, i.e. the NYHA class, ventricular pump function and aerobic performance is sometimes difficult to estabilish. MATERIALS AND METHODS: In 60 elderly with systolic heart failure (75 +/- 3 years, EF 30 +/- 6%), we correlated symptoms (i.e. NYHA class) with [1] degree of functional mitral regurgitation (FMR) determined by color-Doppler echocardiography; [2] degree of left ventricular diastolic dysfunction, measured by Doppler analysis of transmitralic and pulmonary veins flow; [3] VO2 and VE/VCO2 at peak exercise at cardiopulmonary test. RESULTS: In all patients, NYHA class was only weakly related with EF and peak VO2, with wide overlap of individual values among patients with different NYHA class. Instead, we observed a tight relationship between NYHA class, FMR degree, and severity of diastolic dysfunction and VE/VCO2 ratio at peak exercise (p
| Original language | Italian |
|---|---|
| Pages (from-to) | 84-90 |
| Number of pages | 7 |
| Journal | Monaldi Archives for Chest Disease - Cardiac Series |
| Volume | 72 |
| Issue number | 2 |
| Publication status | Published - Jun 2009 |
Fingerprint
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
Cite this
Determinanti della classe NYHA nel paziente anziano con scompenso cardiaco : ruolo della disfunzione diastolica, dell'insufficienza mitralica funzionale e dell'alterata ventilazione durante esercizio. / Malfatto, Gabriella; Cuoccio, Paola; Bizzi, Caterina; Branzi, Giovanna; Villani, Alessandra; Della Rosa, Francesco; Parati, Gianfranco; Facchini, Mario.
In: Monaldi Archives for Chest Disease - Cardiac Series, Vol. 72, No. 2, 06.2009, p. 84-90.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Determinanti della classe NYHA nel paziente anziano con scompenso cardiaco
T2 - ruolo della disfunzione diastolica, dell'insufficienza mitralica funzionale e dell'alterata ventilazione durante esercizio.
AU - Malfatto, Gabriella
AU - Cuoccio, Paola
AU - Bizzi, Caterina
AU - Branzi, Giovanna
AU - Villani, Alessandra
AU - Della Rosa, Francesco
AU - Parati, Gianfranco
AU - Facchini, Mario
PY - 2009/6
Y1 - 2009/6
N2 - BACKGROUND: Color-Doppler ecocardiography and cardiopulmonary stress test are pivotal in the evaluation of patients with heart failure. Besides determining systolic function through left ventricular ejection fraction (EF), color-Doppler ecocardiography evaluates the presence and degree of functional mitral regurgitation and the severity of diastolic dysfunction. Moreover, in addition to the aerobic capacity indicated by peak O2 consumption, other parameters of cardiopulmonary stress have proven useful for diagnostic purposes, such as the peak VE/VCO2 ratio or ventilatory efficiency. Since in elderly patients with heart failure the functional impairment often is a combination of the effects of aging with those of disease, the relationship between symptoms, i.e. the NYHA class, ventricular pump function and aerobic performance is sometimes difficult to estabilish. MATERIALS AND METHODS: In 60 elderly with systolic heart failure (75 +/- 3 years, EF 30 +/- 6%), we correlated symptoms (i.e. NYHA class) with [1] degree of functional mitral regurgitation (FMR) determined by color-Doppler echocardiography; [2] degree of left ventricular diastolic dysfunction, measured by Doppler analysis of transmitralic and pulmonary veins flow; [3] VO2 and VE/VCO2 at peak exercise at cardiopulmonary test. RESULTS: In all patients, NYHA class was only weakly related with EF and peak VO2, with wide overlap of individual values among patients with different NYHA class. Instead, we observed a tight relationship between NYHA class, FMR degree, and severity of diastolic dysfunction and VE/VCO2 ratio at peak exercise (p
AB - BACKGROUND: Color-Doppler ecocardiography and cardiopulmonary stress test are pivotal in the evaluation of patients with heart failure. Besides determining systolic function through left ventricular ejection fraction (EF), color-Doppler ecocardiography evaluates the presence and degree of functional mitral regurgitation and the severity of diastolic dysfunction. Moreover, in addition to the aerobic capacity indicated by peak O2 consumption, other parameters of cardiopulmonary stress have proven useful for diagnostic purposes, such as the peak VE/VCO2 ratio or ventilatory efficiency. Since in elderly patients with heart failure the functional impairment often is a combination of the effects of aging with those of disease, the relationship between symptoms, i.e. the NYHA class, ventricular pump function and aerobic performance is sometimes difficult to estabilish. MATERIALS AND METHODS: In 60 elderly with systolic heart failure (75 +/- 3 years, EF 30 +/- 6%), we correlated symptoms (i.e. NYHA class) with [1] degree of functional mitral regurgitation (FMR) determined by color-Doppler echocardiography; [2] degree of left ventricular diastolic dysfunction, measured by Doppler analysis of transmitralic and pulmonary veins flow; [3] VO2 and VE/VCO2 at peak exercise at cardiopulmonary test. RESULTS: In all patients, NYHA class was only weakly related with EF and peak VO2, with wide overlap of individual values among patients with different NYHA class. Instead, we observed a tight relationship between NYHA class, FMR degree, and severity of diastolic dysfunction and VE/VCO2 ratio at peak exercise (p
UR - http://www.scopus.com/inward/record.url?scp=73949113631&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=73949113631&partnerID=8YFLogxK
M3 - Articolo
C2 - 19947190
VL - 72
SP - 84
EP - 90
JO - Monaldi Archives for Chest Disease
JF - Monaldi Archives for Chest Disease
SN - 1122-0643
IS - 2
ER -