What's hot in inflammatory bowel disease in 2011?

Silvio Danese

Research output: Contribution to journalArticlepeer-review


Ulcerative colitis and Crohn's disease (CD) are the two major forms of inflammatory bowel disease (IBD). In this highlight topic series of articles, the most recent advances in the IBD field are reviewed, especially the newly described cytokines, including the therapeutic implications for their manipulation. In addition, the interplay between the intestinal microbiota and the host is reviewed, including the role of defensins and dysbiosis in CD pathogenesis. Finally, the importance of the non immune systems such as endothelial cells and the hemostatic system are highlighted as new players in IBD pathogenesis.

Original languageEnglish
Pages (from-to)545-546
Number of pages2
JournalWorld Journal of Gastroenterology
Issue number5
Publication statusPublished - Feb 7 2011


  • Crohn's disease
  • Immunology
  • Inflammatory bowel disease
  • Pathogenesis
  • Ulcerative colitis

ASJC Scopus subject areas

  • Gastroenterology


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