Quando due farmaci sono meglio di uno?

Translated title of the contribution: When are two drugs better than one?

I. Bonomi, G. Yannuzzi, E. Perucca

Research output: Contribution to journalArticle

Abstract

All too often medical practice has been adversely affected by acrytical acceptance of indications based on attractive hypotheses rather than scientific evidence. The monotherapy-polytherapy controversy is a good example. From the initial enthusiasm for the never demonstrated advantages of combining different drugs at low dosages the pendulum swang almost to the demonization of polytherapy before returning recently to the ill-defined concept of rational polytherapy. In fact, therapeutic practice can only be based on evaluation of the individual characteristics of the patient and available scientific evidence: monotherapy and polytherapy are not incompatible strategies, but complementary approaches whose utilization is bound to improve with advances in knowledge.

Original languageItalian
Pages (from-to)333-335
Number of pages3
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number106-107
Publication statusPublished - 1999

Fingerprint

Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Quando due farmaci sono meglio di uno? / Bonomi, I.; Yannuzzi, G.; Perucca, E.

In: Bollettino - Lega Italiana contro l'Epilessia, No. 106-107, 1999, p. 333-335.

Research output: Contribution to journalArticle

Bonomi, I. ; Yannuzzi, G. ; Perucca, E. / Quando due farmaci sono meglio di uno?. In: Bollettino - Lega Italiana contro l'Epilessia. 1999 ; No. 106-107. pp. 333-335.
@article{93f8b109dfd84f17aeca840259a2b3cf,
title = "Quando due farmaci sono meglio di uno?",
abstract = "All too often medical practice has been adversely affected by acrytical acceptance of indications based on attractive hypotheses rather than scientific evidence. The monotherapy-polytherapy controversy is a good example. From the initial enthusiasm for the never demonstrated advantages of combining different drugs at low dosages the pendulum swang almost to the demonization of polytherapy before returning recently to the ill-defined concept of rational polytherapy. In fact, therapeutic practice can only be based on evaluation of the individual characteristics of the patient and available scientific evidence: monotherapy and polytherapy are not incompatible strategies, but complementary approaches whose utilization is bound to improve with advances in knowledge.",
keywords = "Drug treatment, Epilepsy, Monotherapy, Polytherapy",
author = "I. Bonomi and G. Yannuzzi and E. Perucca",
year = "1999",
language = "Italian",
pages = "333--335",
journal = "Bollettino - Lega Italiana contro l'Epilessia",
issn = "0394-560X",
publisher = "Lega Italiana contro l'Epilessia",
number = "106-107",

}

TY - JOUR

T1 - Quando due farmaci sono meglio di uno?

AU - Bonomi, I.

AU - Yannuzzi, G.

AU - Perucca, E.

PY - 1999

Y1 - 1999

N2 - All too often medical practice has been adversely affected by acrytical acceptance of indications based on attractive hypotheses rather than scientific evidence. The monotherapy-polytherapy controversy is a good example. From the initial enthusiasm for the never demonstrated advantages of combining different drugs at low dosages the pendulum swang almost to the demonization of polytherapy before returning recently to the ill-defined concept of rational polytherapy. In fact, therapeutic practice can only be based on evaluation of the individual characteristics of the patient and available scientific evidence: monotherapy and polytherapy are not incompatible strategies, but complementary approaches whose utilization is bound to improve with advances in knowledge.

AB - All too often medical practice has been adversely affected by acrytical acceptance of indications based on attractive hypotheses rather than scientific evidence. The monotherapy-polytherapy controversy is a good example. From the initial enthusiasm for the never demonstrated advantages of combining different drugs at low dosages the pendulum swang almost to the demonization of polytherapy before returning recently to the ill-defined concept of rational polytherapy. In fact, therapeutic practice can only be based on evaluation of the individual characteristics of the patient and available scientific evidence: monotherapy and polytherapy are not incompatible strategies, but complementary approaches whose utilization is bound to improve with advances in knowledge.

KW - Drug treatment

KW - Epilepsy

KW - Monotherapy

KW - Polytherapy

UR - http://www.scopus.com/inward/record.url?scp=0033500914&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033500914&partnerID=8YFLogxK

M3 - Articolo

AN - SCOPUS:0033500914

SP - 333

EP - 335

JO - Bollettino - Lega Italiana contro l'Epilessia

JF - Bollettino - Lega Italiana contro l'Epilessia

SN - 0394-560X

IS - 106-107

ER -