When patients are rendered normotensive

G. Mancia, A. Lafranchi, B. N. Cattaneo, G. Grassi

Research output: Contribution to journalArticlepeer-review


Hypertension is usually symptomless and associated with little or no alterations in well-being. However, conclusive evidence demonstrates that hypertension is a major risk factor for cardiovascular disease, A reduction of the elevated blood pressure with antihypertensive medication can reduce this risk, but not to that of a normotensive patient, Furthermore, antihypertensive treatment is more effective against stroke and congestive heart failure than against coronary heart disease. Antihypertensive treatment is costly due to its extensive use and life-long indication. Future progress in this area will aim to identify those hypertensive patients at greatest risk of cardiovascular disease, in order to limit treatment to those patients who may benefit most. This paper will consider the effects of blood pressure reduction on cardiovascular morbidity and mortality, the differing effects of antihypertensive treatment on the complications of hypertension, and how antihypertensive therapy can be optimized.

Original languageEnglish
Pages (from-to)58-64
Number of pages7
Issue numberSUPPL. 1
Publication statusPublished - 1994


  • Antihypertensive treatment
  • Cardiovascular disease
  • Hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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