When phylogenetic analysis complements the epidemiological investigation: A case of HIV-2 infection, Italy

Massimo Ciccozzi, Annapaola Callegaro, Alessandra Lo Presti, Eleonora Cella, Marta Giovanetti, Romina Salpini, Muhammed Babakir-Mina, Claudio Farina, Franco Maggiolo, Carlo Federico Perno, Marco Ciotti

Research output: Contribution to journalArticle

Abstract

Human immunodeficiency virus type 2 (HIV-2) infection is geographically restricted, affecting West African countries such as Guinea- Bissau and Cape Verde. We describe a recent case of HIV-2 infection in an Italian patient. Phylogenetic analysis of the V3 region of HIV-2 indicated that the Italian patient was infected by HIV-2 subtype A2. The sequence obtained from the Italian patient clustered significantly with a sequence isolated from Senegal. A phylogenetic doubt may arise from a Guinea Bissau sequence because it was in a major clade with the Italian and Senegal sequences, but was not statistically significant. The discovery of another Italian case over a short time frame stresses the importance of strengthening the surveillance system for HIV-2 because of the increase in migration from endemic areas to Italy.

Original languageEnglish
Pages (from-to)93-96
Number of pages4
JournalNew Microbiologica
Volume36
Issue number1
Publication statusPublished - 2013

Keywords

  • HIV-2
  • Italian patient
  • Phylogenesis

ASJC Scopus subject areas

  • Microbiology (medical)

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    Ciccozzi, M., Callegaro, A., Presti, A. L., Cella, E., Giovanetti, M., Salpini, R., Babakir-Mina, M., Farina, C., Maggiolo, F., Perno, C. F., & Ciotti, M. (2013). When phylogenetic analysis complements the epidemiological investigation: A case of HIV-2 infection, Italy. New Microbiologica, 36(1), 93-96.