Which factors influence onset and latency to treatment in generalized anxiety disorder, panic disorder, and obsessive–compulsive disorder?

Beatrice Benatti, Giulia Camuri, Bernardo Dell’Osso, Laura Cremaschi, Ester Sembira, Carlotta Palazzo, Lucio Oldani, Cristina Dobrea, Chiara Arici, Diego Primavera, Bernardo Carpiniello, Filippo Castellano, Giuseppe Carrà, Massimo Clerici, David S. Baldwin, Alfredo Carlo Altamura

Research output: Contribution to journalArticle

Abstract

Anxiety disorders are common, comorbid, and disabling conditions, often underdiagnosed and under-treated, typically with an early onset, chronic course, and prolonged duration of untreated illness. The present study aimed to explore the influence of sociodemographic and clinical factors in relation to onset and latency to treatment in patients with generalized anxiety disorder (GAD), panic disorder (PD), and obsessive–compulsive disorder (OCD). A total of 157 patients with a Diagnostic and Statistical Manual of Mental Disorders, 4th ed. Text Revision (DSM-IV-TR) diagnosis of PD (n=49), GAD (n=68), and OCD (n=40) were recruited, and epidemiological and clinical variables were collected through a specific questionnaire. Statistical analyses were carried out to compare variables across diagnostic groups. PD, GAD, and OCD patients showed a duration of untreated illness of 53.9±81.5, 77.47±95.76, and 90.6±112.1 months, respectively. Significant differences between groups were found with respect to age, age of first diagnosis, age of first treatment, family history of psychiatric illness, onset-related stressful events, benzodiazepine prescription as first treatment, antidepressant prescription as first treatment, and help-seeking (self-initiated vs. initiated by others). Patients with GAD, PD, and OCD showed significant differences in factors influencing onset and latency to treatment, which may, in turn, affect condition-related outcome and overall prognosis. Further studies with larger samples are warranted in the field.

Original languageEnglish
Pages (from-to)347-352
Number of pages6
JournalInternational Clinical Psychopharmacology
Volume31
Issue number6
DOIs
Publication statusPublished - 2016

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Pharmacology (medical)

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    Benatti, B., Camuri, G., Dell’Osso, B., Cremaschi, L., Sembira, E., Palazzo, C., Oldani, L., Dobrea, C., Arici, C., Primavera, D., Carpiniello, B., Castellano, F., Carrà, G., Clerici, M., Baldwin, D. S., & Altamura, A. C. (2016). Which factors influence onset and latency to treatment in generalized anxiety disorder, panic disorder, and obsessive–compulsive disorder? International Clinical Psychopharmacology, 31(6), 347-352. https://doi.org/10.1097/YIC.0000000000000137