Whipple's disease

Federico Biagi, Lucia Trotta, Gino R. Corazza

Research output: Contribution to journalArticlepeer-review


Whipple's disease is a chronic multisystemic infection, due to Tropheryma whipplei, a bacterium ubiquitously present in the environment. Although it is very rare, its clinical features are non-specific and can affect several different districts. Whipple's disease is therefore a condition that should always be kept in mind by doctors working in several branches of medicine, such as internal medicine, gastroenterology, rheumatology, neurology, and cardiology. The condition is fatal if not promptly recognized and treated, but the best treatment is still not completely defined, especially in relapsing disease, neurological manifestations, and in cases of immunoreconstitution after initiation of antibiotic treatment.

Original languageEnglish
Pages (from-to)209-213
Number of pages5
JournalInternal and Emergency Medicine
Issue numberSUPPL. 3
Publication statusPublished - Oct 2012


  • Immune reconstitution syndrome
  • Tropheryma whipplei
  • Whipple's disease

ASJC Scopus subject areas

  • Emergency Medicine
  • Internal Medicine


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