TY - JOUR
T1 - White matter lesion detection in multiple sclerosis
T2 - Improved interobserver concordance with multispectral MRI display
AU - Brunetti, Arturo
AU - Tedeschi, Gioacchino
AU - Di Costanzo, Alfonso
AU - Covelli, Eugenio Maria
AU - Aloj, Luigi
AU - Bonavita, Simona
AU - Ciarmiello, Andrea
AU - Alfano, Bruno
AU - Salvatore, Marco
PY - 1997
Y1 - 1997
N2 - An assessment of the detectability of white matter lesions and of concordance between observers with different levels of MRI reading experience was performed with comparative evaluation of spin-echo MRI images and of corresponding 'multispectral' maps in 16 patients with definite multiple sclerosis (MS). Multispectral maps were obtained by means of a recently described post-processing technique based on the simultaneous display of MRI parameters and a standardized colour scale with red, green and blue coding for relaxation rates R1 and R2 and proton density, respectively. Spin-echo images on films and multispectral maps displayed on a personal computer were randomly rated at 2-month intervals. Interobserver concordance (k-test) was assessed among three readers with different levels of MRI experience (an experienced neuroradiologist, a radiology resident and a neurologist). For multispectral maps we found increased interobserver concordance with the experienced neuroradiologist (multispectral vs conventional images: k = 0.77 vs 0.66 for the radiology resident and 0.66 vs 0.56 for the neurologist), an increased number of detected lesions and decreased reading time. Multispectral maps permit easy detection of MS lesions and may improve interobserver concordance compared with conventional spin-echo studies.
AB - An assessment of the detectability of white matter lesions and of concordance between observers with different levels of MRI reading experience was performed with comparative evaluation of spin-echo MRI images and of corresponding 'multispectral' maps in 16 patients with definite multiple sclerosis (MS). Multispectral maps were obtained by means of a recently described post-processing technique based on the simultaneous display of MRI parameters and a standardized colour scale with red, green and blue coding for relaxation rates R1 and R2 and proton density, respectively. Spin-echo images on films and multispectral maps displayed on a personal computer were randomly rated at 2-month intervals. Interobserver concordance (k-test) was assessed among three readers with different levels of MRI experience (an experienced neuroradiologist, a radiology resident and a neurologist). For multispectral maps we found increased interobserver concordance with the experienced neuroradiologist (multispectral vs conventional images: k = 0.77 vs 0.66 for the radiology resident and 0.66 vs 0.56 for the neurologist), an increased number of detected lesions and decreased reading time. Multispectral maps permit easy detection of MS lesions and may improve interobserver concordance compared with conventional spin-echo studies.
KW - Image processing
KW - Magnetic resonance imaging
KW - Multiple sclerosis
KW - Multispectral display
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U2 - 10.1007/s004150050148
DO - 10.1007/s004150050148
M3 - Article
C2 - 9352457
AN - SCOPUS:0030719874
VL - 244
SP - 586
EP - 590
JO - Journal of Neurology
JF - Journal of Neurology
SN - 0340-5354
IS - 9
ER -