Whole blood fatty acid composition at birth: From the maternal compartment to the infant

Carlo Agostoni, Claudio Galli, Enrica Riva, Patrizia Risé, Claudio Colombo, Marcello Giovannini, Franca Marangoni

Research output: Contribution to journalArticlepeer-review


Background & aims: The biological role of fatty acids (FA) in the perinatal period is under active investigation. We here describe the application of a simplified microanalytical procedure to compare the FA profile of maternal, umbilical cord and infant whole blood, inclusive of all circulating lipid fractions and cells. Methods: The FA composition has been analyzed with a micromethod in 16 triplets, including maternal blood, cord blood at delivery and infant blood at day 4, respectively. Results: As expected, the FA composition of blood samples withdrawn from the umbilical cord is more similar to the FA composition of blood from 4-day old infants than the FA pattern of maternal blood at delivery. Nevertheless, infant blood FA profile differed from cord for lower long-chain polyunsaturated FA and higher monounsaturated FA. Conclusions: Our explorative data using whole blood microanalysis confirm the progressive increase of long-chain polyunsaturated FA levels from the mothers towards cord and then infant blood.

Original languageEnglish
Pages (from-to)503-505
Number of pages3
JournalClinical Nutrition
Issue number4
Publication statusPublished - Aug 2011


  • Cord blood
  • Fatty acids
  • Long-chain polyunsaturated fatty acids
  • Newborn infants
  • Pregnancy

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Nutrition and Dietetics


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