TY - JOUR
T1 - Whole-body FDG PET-MR oncologic imaging
T2 - pitfalls in clinical interpretation related to inaccurate MR-based attenuation correction
AU - Attenberger, Ulrike
AU - Catana, Ciprian
AU - Chandarana, Hersh
AU - Catalano, Onofrio A.
AU - Friedman, Kent
AU - Schonberg, Stefan A.
AU - Thrall, James
AU - Salvatore, Marco
AU - Rosen, Bruce R.
AU - Guimaraes, Alexander R.
PY - 2015/5/30
Y1 - 2015/5/30
N2 - Simultaneous data collection for positron emission tomography and magnetic resonance imaging (PET/MR) is now a reality. While the full benefits of concurrently acquiring PET and MR data and the potential added clinical value are still being evaluated, initial studies have identified several important potential pitfalls in the interpretation of fluorodeoxyglucose (FDG) PET/MRI in oncologic whole-body imaging, the majority of which being related to the errors in the attenuation maps created from the MR data. The purpose of this article was to present such pitfalls and artifacts using case examples, describe their etiology, and discuss strategies to overcome them. Using a case-based approach, we will illustrate artifacts related to (1) Inaccurate bone tissue segmentation; (2) Inaccurate air cavities segmentation; (3) Motion-induced misregistration; (4) RF coils in the PET field of view; (5) B0 field inhomogeneity; (6) B1 field inhomogeneity; (7) Metallic implants; (8) MR contrast agents.
AB - Simultaneous data collection for positron emission tomography and magnetic resonance imaging (PET/MR) is now a reality. While the full benefits of concurrently acquiring PET and MR data and the potential added clinical value are still being evaluated, initial studies have identified several important potential pitfalls in the interpretation of fluorodeoxyglucose (FDG) PET/MRI in oncologic whole-body imaging, the majority of which being related to the errors in the attenuation maps created from the MR data. The purpose of this article was to present such pitfalls and artifacts using case examples, describe their etiology, and discuss strategies to overcome them. Using a case-based approach, we will illustrate artifacts related to (1) Inaccurate bone tissue segmentation; (2) Inaccurate air cavities segmentation; (3) Motion-induced misregistration; (4) RF coils in the PET field of view; (5) B0 field inhomogeneity; (6) B1 field inhomogeneity; (7) Metallic implants; (8) MR contrast agents.
KW - Attenuation correction
KW - PET/MRI
KW - Pitfalls
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U2 - 10.1007/s00261-015-0455-3
DO - 10.1007/s00261-015-0455-3
M3 - Article
C2 - 26025348
AN - SCOPUS:84938975892
VL - 40
SP - 1374
EP - 1386
JO - Abdominal Imaging
JF - Abdominal Imaging
SN - 0942-8925
IS - 6
ER -