Whole-body magnetic resonance imaging (WB-MRI) in lymphoma: State of the art

Domenico Albano, Alberto Bruno, Caterina Patti, Giuseppe Micci, Massimo Midiri, Corrado Tarella, Massimo Galia

Research output: Contribution to journalReview articlepeer-review

Abstract

The improvements in magnetic resonance imaging (MRI) technology and the concern related to the increased cancer risk in patients with lymphoma, also due to radiation exposure associated with imaging examinations, have led to the introduction of whole-body MRI (WB-MRI) as a radiation-free alternative to standard imaging procedures. WB-MRI seems a less histology-dependent functional imaging test than 18 F-fluorodeoxyglucose-positron emission tomography/CT (18 F-FDG-PET/CT). In patients with FDG-avid lymphomas, such as diffuse large B-cell lymphoma (DLBCL) and Hodgkin lymphoma (HL), 18 F-FDG-PET/CT remains the imaging reference standard for staging, with WB-MRI potentially being a complementary modality that could replace CT, especially in young patients. On the other hand, WB-MRI is a valuable imaging procedure for lymphoma surveillance and in lymphomas with variable/low FDG avidity and nonfollicular indolent lymphomas. The aim of this paper is to discuss the current state of the art of WB-MRI in lymphoma by evaluating its diagnostic performance in different lymphoma subtypes: Hodgkin, aggressive, and indolent lymphomas.

Original languageEnglish
Pages (from-to)12-21
Number of pages10
JournalHematological Oncology
Volume38
Issue number1
Early online dateSep 5 2019
DOIs
Publication statusPublished - 2020

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