Whole-body magnetic resonance imaging (WB-MRI) in lymphoma: State of the art: Hematological Oncology

D. Albano, A. Bruno, C. Patti, G. Micci, M. Midiri, C. Tarella, M. Galia

Research output: Contribution to journalArticlepeer-review


The improvements in magnetic resonance imaging (MRI) technology and the concern related to the increased cancer risk in patients with lymphoma, also due to radiation exposure associated with imaging examinations, have led to the introduction of whole-body MRI (WB-MRI) as a radiation-free alternative to standard imaging procedures. WB-MRI seems a less histology-dependent functional imaging test than 18F-fluorodeoxyglucose-positron emission tomography/CT (18F-FDG-PET/CT). In patients with FDG-avid lymphomas, such as diffuse large B-cell lymphoma (DLBCL) and Hodgkin lymphoma (HL), 18F-FDG-PET/CT remains the imaging reference standard for staging, with WB-MRI potentially being a complementary modality that could replace CT, especially in young patients. On the other hand, WB-MRI is a valuable imaging procedure for lymphoma surveillance and in lymphomas with variable/low FDG avidity and nonfollicular indolent lymphomas. The aim of this paper is to discuss the current state of the art of WB-MRI in lymphoma by evaluating its diagnostic performance in different lymphoma subtypes: Hodgkin, aggressive, and indolent lymphomas. © 2019 John Wiley & Sons, Ltd.
Original languageEnglish
Pages (from-to)12-21
Number of pages10
JournalHematol. Oncol.
Issue number1
Publication statusPublished - 2020


  • lymphoma
  • magnetic resonance imaging
  • positron emission tomography
  • whole-body imaging
  • contrast medium
  • fluorodeoxyglucose f 18
  • gadolinium
  • radiopharmaceutical agent
  • rituximab
  • anaplastic large cell lymphoma
  • apparent diffusion coefficient
  • B cell lymphoma
  • cancer staging
  • diffuse large B cell lymphoma
  • diffusion weighted imaging
  • follicular lymphoma
  • gastrointestinal lymphoma
  • Hodgkin disease
  • human
  • intermethod comparison
  • mantle cell lymphoma
  • peripheral T cell lymphoma
  • positron emission tomography-computed tomography
  • predictive value
  • priority journal
  • radiation exposure
  • Review
  • T cell lymphoma
  • treatment response
  • whole body MRI
  • animal
  • nuclear magnetic resonance imaging
  • procedures
  • whole body imaging
  • Animals
  • Humans
  • Lymphoma
  • Magnetic Resonance Imaging
  • Neoplasm Staging
  • Whole Body Imaging


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