Whole-body vibration as antihypertensive non-pharmacological treatment in hypertensive individuals with knee osteoarthritis: Randomized cross-over trial

Eloá Moreira-Marconi, Vanessa da Silva Caiado, Ygor Teixeira-Silva, Alexandre Gonçalves de Meirelles, Marcia Cristina Moura-Fernandes, Patrícia Lopes-Souza, Aline Reis-Silva, Danúbia C. Sá-Caputo, Laisa L. Paineiras-Domingos, Ana Cristina Rodrigues Lacerda, Vanessa Amaral Mendonça, Ricardo Gonçalves Cordeiro, Redha Taiar, Alessandro Sartorio, Alexei Wong, Borja Sañudo, Mario Bernardo-Filho

Research output: Contribution to journalArticlepeer-review


(1) Background: Hypertension is a serious medical condition characterized by a persistent increase in blood pressure (BP), which is prevalent in individuals with knee osteoarthritis (KOA). Pharmacological interventions are normally used to treat both hypertension and KOA; however, a more sustainable form of treatment is desirable for these clinical conditions. Whole-body vibration (WBV) exercise has been proposed as a non-pharmacological therapy for reducing both BP and KOA symptomatology. This study aimed to evaluate the antihypertensive effect of WBV in hypertensive individuals with KOA. (2) Methods: Nineteen hypertensive individuals with KOA were randomly allocated to either a control (CG) (n = 9) or a WBV group (WBVG) (n = 10). Subjects in the WBVG were positioned sitting in a chair in front of a vibrating platform (VP) with the feet on the base (peak-to-peak displacement 2.5, 5.0 and 7.5 mm; frequencies 5 to 14 Hz). In the CG, subjects assumed the same position with the VP turned off. The protocols in the CG and WBVG were performed 2 days/week for a total of 5 weeks. (3) Results: No baseline differences (age, anthropometrics, BP parameters and medications) between the groups were found (p > 0.05). WBV exercise reduced systolic BP (SBP: 126.1 ± 2.7 versus 119.1 ± 3.2 mmHg; p = 0.001; post hoc: p = 0.02; F = 23.97) and mean BP (MBP: 82.6 ± 1.8 versus 78.7 ± 1.8, p = 0.001, post hoc: p = 0.02; F = 23.97), while no significant changes were found in diastolic BP (DBP: 68.5 ± 2.2 versus 64.4 ± 2.3; p = 0.11; F = 2.68). (4) Conclusions: WBV might be considered a sustainable therapy for exerting an antihypertensive effect in medicated hypertensive individuals with KOA. This decline in BP might translate to a reduction in pharmacological need, although further studies are necessary to understand the mechanisms underlying the described effect.

Original languageEnglish
Article number8944
Pages (from-to)1-13
Number of pages13
JournalSustainability (Switzerland)
Issue number21
Publication statusPublished - Nov 1 2020


  • Hypertension
  • Knee osteoarthritis
  • Non-pharmacological treatment
  • Physical and rehabilitation medicine
  • Sustainability
  • Whole-body vibration

ASJC Scopus subject areas

  • Geography, Planning and Development
  • Renewable Energy, Sustainability and the Environment
  • Management, Monitoring, Policy and Law


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