Whole-genome sequencing of drug-resistant Mycobacterium tuberculosis strains, Tunisia, 2012-2016

Imen Bouzouita, Andrea Maurizio Cabibbe, Alberto Trovato, Henda Daroui, Asma Ghariani, Basma Midouni, Leila Essalah, Emna Mehiri, Daniela Maria Cirillo, Leila Slim Saidi

Research output: Contribution to journalArticlepeer-review

Abstract

To investigate transmission of drug-resistant strains of Mycobacterium tuberculosis in Tunisia, we performed whole-genome sequencing on 46 multidrug-resistant strains isolated during 2012-2016. Core-genome multilocus sequence typing grouped 30 (65.2%) strains into 3 clusters, indicating extensive recent transmission and Haarlem clone predominance. Whole-genome sequencing might help public health services undertake appropriate control actions.

Original languageEnglish
Pages (from-to)547-550
Number of pages4
JournalEmerging Infectious Diseases
Volume25
Issue number3
DOIs
Publication statusPublished - Mar 2019

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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