Widespread Livedoid Vasculopathy

Angelo V. Marzano, Miriam Vanotti, Elvio Alessi

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A 37-year-old woman with a 13-year history of widespread livedo reticularis and recurrent, painful ulcerative skin lesions was referred to our department because of a relapse of cutaneous manifestations of the skin lesions involving almost the whole body surface; malar erythema and oedema, non-scarring alopecia and fever were also associated. Routine laboratory data, immunological investigations and coagulation parameters were normal or negative. Histology was consistent with livedoid vasculopathy. A good clinical response was obtained using intravenous methylprednisolone combined with pentoxifylline. Livedoid vasculopathy is a rare, distinctive dermatosis that can be associated with systemic autoimmune disorders or present in an "idiopathic" form. The latter is at present regarded as a non-inflammatory thrombotic disease that may occur in patients with coagulation abnormalities. It is noteworthy that, in the present case, despite long-standing and dramatic cutaneous features, serious systemic complications have not developed and the patient's seroimmunologic and coagulative profile has remained normal.

Original languageEnglish
Pages (from-to)457-460
Number of pages4
JournalActa Dermato-Venereologica
Volume83
Issue number6
DOIs
Publication statusPublished - 2003

Fingerprint

relapse
Disease
Skin
present
history
Livedo Reticularis
Skin Manifestations
Pentoxifylline
Alopecia
Methylprednisolone
Erythema
Skin Diseases
Edema
Histology
Fever
Recurrence
Lesion
History
Complications
Relapse

Keywords

  • Autoimmune diseases
  • Coagulation abnormalities
  • Livedoid vasculopathy

ASJC Scopus subject areas

  • Dermatology

Cite this

Widespread Livedoid Vasculopathy. / Marzano, Angelo V.; Vanotti, Miriam; Alessi, Elvio.

In: Acta Dermato-Venereologica, Vol. 83, No. 6, 2003, p. 457-460.

Research output: Contribution to journalArticle

Marzano, Angelo V. ; Vanotti, Miriam ; Alessi, Elvio. / Widespread Livedoid Vasculopathy. In: Acta Dermato-Venereologica. 2003 ; Vol. 83, No. 6. pp. 457-460.
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