Withdrawal of phenobarbital and carbamazepine in epileptic patients

A preliminary neuropsychological report

R. Gallassi, S. Lorusso, A. Stracciari, A. Morreale, G. Procaccianti, A. Baruzzi

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

We systematically investigated the neuropsychological effects of controlled withdrawal of antiepileptic therapy with a battery of tests exploring intelligence, vigilance, attention, memory and sonsori-motor performance. 16 patients without seizures for at least 2 years, 9 on therapy with phenobarbital (PB) and 7 with carbamazepine (CBZ), were examined 4 times over a period of 21 months. No significant correlation was found between drug levels and performance in the tests. The slight differences found between the PB and CBZ groups at full doses disappeared completely one year after withdrawal.

Original languageEnglish
Pages (from-to)59-62
Number of pages4
JournalActa Neurologica Scandinavica
Volume74
Issue number1
Publication statusPublished - 1986

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Carbamazepine
Phenobarbital
Intelligence Tests
Anticonvulsants
Seizures
Therapeutics
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Withdrawal of phenobarbital and carbamazepine in epileptic patients : A preliminary neuropsychological report. / Gallassi, R.; Lorusso, S.; Stracciari, A.; Morreale, A.; Procaccianti, G.; Baruzzi, A.

In: Acta Neurologica Scandinavica, Vol. 74, No. 1, 1986, p. 59-62.

Research output: Contribution to journalArticle

Gallassi, R, Lorusso, S, Stracciari, A, Morreale, A, Procaccianti, G & Baruzzi, A 1986, 'Withdrawal of phenobarbital and carbamazepine in epileptic patients: A preliminary neuropsychological report', Acta Neurologica Scandinavica, vol. 74, no. 1, pp. 59-62.
Gallassi, R. ; Lorusso, S. ; Stracciari, A. ; Morreale, A. ; Procaccianti, G. ; Baruzzi, A. / Withdrawal of phenobarbital and carbamazepine in epileptic patients : A preliminary neuropsychological report. In: Acta Neurologica Scandinavica. 1986 ; Vol. 74, No. 1. pp. 59-62.
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