Within-visit BP variability, cardiovascular risk factors, and BP control in central and eastern Europe

Findings from the BP-CARE study

Guido Grassi, Gino Seravalle, Alessandro Maloberti, Rita Facchetti, Cesare Cuspidi, Michele Bombelli, Stephane Laurent, Josep Redon, Giuseppe Mancia

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Introduction and objective: Blood pressure variability (BPV) within 24 h or between visits has been found to represent an independent risk factor for cardiovascular disease. The present study was aimed at determining whether a clinical significance can be given also to the BP variations occurring within a single clinical visit. Methods: BPV was quantified as coefficient of variation and as standard deviation (SD) of the mean of three systolic SBP values within a visit in the context of a largecross subclinical survey (BP-CARE) of treated hypertensive patients living in Eastern European countries. The study population was divided into coefficient of variation and SD quartiles and for each quartile a relationship was sought with a large number of cardiovascular risk factors based on patients' history, physical and laboratory examinations. Results: The 6425 hypertensive patients had an age of 59.2±11 years (mean±SD); they were equally distributed by sex and displayed an average SD and coefficient of variation amounting to 5.1±6.2mmHg and 3.5±4.0%, respectively. Compared with the lowest coefficient of variation quartile (Q1), patients in the highest quartile (Q4) showed a significantly greater prevalence of several cardiovascular risk factors, such as age (Q1: 58.5±11 vs. Q4: 60.3±11 years, P

Original languageEnglish
Pages (from-to)2250-2256
Number of pages7
JournalJournal of Hypertension
Volume33
Issue number11
DOIs
Publication statusPublished - 2015

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Eastern Europe
Blood Pressure
Physical Examination
Cardiovascular Diseases
History
Population

Keywords

  • Ambulatory BP
  • BP variability
  • Cardiovascular risk
  • Clinic blood pressure
  • Metabolic profile

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Within-visit BP variability, cardiovascular risk factors, and BP control in central and eastern Europe : Findings from the BP-CARE study. / Grassi, Guido; Seravalle, Gino; Maloberti, Alessandro; Facchetti, Rita; Cuspidi, Cesare; Bombelli, Michele; Laurent, Stephane; Redon, Josep; Mancia, Giuseppe.

In: Journal of Hypertension, Vol. 33, No. 11, 2015, p. 2250-2256.

Research output: Contribution to journalArticle

Grassi, Guido ; Seravalle, Gino ; Maloberti, Alessandro ; Facchetti, Rita ; Cuspidi, Cesare ; Bombelli, Michele ; Laurent, Stephane ; Redon, Josep ; Mancia, Giuseppe. / Within-visit BP variability, cardiovascular risk factors, and BP control in central and eastern Europe : Findings from the BP-CARE study. In: Journal of Hypertension. 2015 ; Vol. 33, No. 11. pp. 2250-2256.
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