Abstract
Introduction and objective: Blood pressure variability (BPV) within 24 h or between visits has been found to represent an independent risk factor for cardiovascular disease. The present study was aimed at determining whether a clinical significance can be given also to the BP variations occurring within a single clinical visit. Methods: BPV was quantified as coefficient of variation and as standard deviation (SD) of the mean of three systolic SBP values within a visit in the context of a largecross subclinical survey (BP-CARE) of treated hypertensive patients living in Eastern European countries. The study population was divided into coefficient of variation and SD quartiles and for each quartile a relationship was sought with a large number of cardiovascular risk factors based on patients' history, physical and laboratory examinations. Results: The 6425 hypertensive patients had an age of 59.2±11 years (mean±SD); they were equally distributed by sex and displayed an average SD and coefficient of variation amounting to 5.1±6.2mmHg and 3.5±4.0%, respectively. Compared with the lowest coefficient of variation quartile (Q1), patients in the highest quartile (Q4) showed a significantly greater prevalence of several cardiovascular risk factors, such as age (Q1: 58.5±11 vs. Q4: 60.3±11 years, P
| Original language | English |
|---|---|
| Pages (from-to) | 2250-2256 |
| Number of pages | 7 |
| Journal | Journal of Hypertension |
| Volume | 33 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 2015 |
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Keywords
- Ambulatory BP
- BP variability
- Cardiovascular risk
- Clinic blood pressure
- Metabolic profile
ASJC Scopus subject areas
- Internal Medicine
- Physiology
- Cardiology and Cardiovascular Medicine
Cite this
Within-visit BP variability, cardiovascular risk factors, and BP control in central and eastern Europe : Findings from the BP-CARE study. / Grassi, Guido; Seravalle, Gino; Maloberti, Alessandro; Facchetti, Rita; Cuspidi, Cesare; Bombelli, Michele; Laurent, Stephane; Redon, Josep; Mancia, Giuseppe.
In: Journal of Hypertension, Vol. 33, No. 11, 2015, p. 2250-2256.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Within-visit BP variability, cardiovascular risk factors, and BP control in central and eastern Europe
T2 - Findings from the BP-CARE study
AU - Grassi, Guido
AU - Seravalle, Gino
AU - Maloberti, Alessandro
AU - Facchetti, Rita
AU - Cuspidi, Cesare
AU - Bombelli, Michele
AU - Laurent, Stephane
AU - Redon, Josep
AU - Mancia, Giuseppe
PY - 2015
Y1 - 2015
N2 - Introduction and objective: Blood pressure variability (BPV) within 24 h or between visits has been found to represent an independent risk factor for cardiovascular disease. The present study was aimed at determining whether a clinical significance can be given also to the BP variations occurring within a single clinical visit. Methods: BPV was quantified as coefficient of variation and as standard deviation (SD) of the mean of three systolic SBP values within a visit in the context of a largecross subclinical survey (BP-CARE) of treated hypertensive patients living in Eastern European countries. The study population was divided into coefficient of variation and SD quartiles and for each quartile a relationship was sought with a large number of cardiovascular risk factors based on patients' history, physical and laboratory examinations. Results: The 6425 hypertensive patients had an age of 59.2±11 years (mean±SD); they were equally distributed by sex and displayed an average SD and coefficient of variation amounting to 5.1±6.2mmHg and 3.5±4.0%, respectively. Compared with the lowest coefficient of variation quartile (Q1), patients in the highest quartile (Q4) showed a significantly greater prevalence of several cardiovascular risk factors, such as age (Q1: 58.5±11 vs. Q4: 60.3±11 years, P
AB - Introduction and objective: Blood pressure variability (BPV) within 24 h or between visits has been found to represent an independent risk factor for cardiovascular disease. The present study was aimed at determining whether a clinical significance can be given also to the BP variations occurring within a single clinical visit. Methods: BPV was quantified as coefficient of variation and as standard deviation (SD) of the mean of three systolic SBP values within a visit in the context of a largecross subclinical survey (BP-CARE) of treated hypertensive patients living in Eastern European countries. The study population was divided into coefficient of variation and SD quartiles and for each quartile a relationship was sought with a large number of cardiovascular risk factors based on patients' history, physical and laboratory examinations. Results: The 6425 hypertensive patients had an age of 59.2±11 years (mean±SD); they were equally distributed by sex and displayed an average SD and coefficient of variation amounting to 5.1±6.2mmHg and 3.5±4.0%, respectively. Compared with the lowest coefficient of variation quartile (Q1), patients in the highest quartile (Q4) showed a significantly greater prevalence of several cardiovascular risk factors, such as age (Q1: 58.5±11 vs. Q4: 60.3±11 years, P
KW - Ambulatory BP
KW - BP variability
KW - Cardiovascular risk
KW - Clinic blood pressure
KW - Metabolic profile
UR - http://www.scopus.com/inward/record.url?scp=84943144479&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84943144479&partnerID=8YFLogxK
U2 - 10.1097/HJH.0000000000000700
DO - 10.1097/HJH.0000000000000700
M3 - Article
C2 - 26372320
AN - SCOPUS:84943144479
VL - 33
SP - 2250
EP - 2256
JO - Journal of Hypertension
JF - Journal of Hypertension
SN - 0263-6352
IS - 11
ER -