Within-visit BP variability, cardiovascular risk factors, and BP control in central and eastern Europe: Findings from the BP-CARE study

Guido Grassi, Gino Seravalle, Alessandro Maloberti, Rita Facchetti, Cesare Cuspidi, Michele Bombelli, Stephane Laurent, Josep Redon, Giuseppe Mancia

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction and objective: Blood pressure variability (BPV) within 24 h or between visits has been found to represent an independent risk factor for cardiovascular disease. The present study was aimed at determining whether a clinical significance can be given also to the BP variations occurring within a single clinical visit. Methods: BPV was quantified as coefficient of variation and as standard deviation (SD) of the mean of three systolic SBP values within a visit in the context of a largecross subclinical survey (BP-CARE) of treated hypertensive patients living in Eastern European countries. The study population was divided into coefficient of variation and SD quartiles and for each quartile a relationship was sought with a large number of cardiovascular risk factors based on patients' history, physical and laboratory examinations. Results: The 6425 hypertensive patients had an age of 59.2±11 years (mean±SD); they were equally distributed by sex and displayed an average SD and coefficient of variation amounting to 5.1±6.2mmHg and 3.5±4.0%, respectively. Compared with the lowest coefficient of variation quartile (Q1), patients in the highest quartile (Q4) showed a significantly greater prevalence of several cardiovascular risk factors, such as age (Q1: 58.5±11 vs. Q4: 60.3±11 years, P

Original languageEnglish
Pages (from-to)2250-2256
Number of pages7
JournalJournal of Hypertension
Volume33
Issue number11
DOIs
Publication statusPublished - 2015

Keywords

  • Ambulatory BP
  • BP variability
  • Cardiovascular risk
  • Clinic blood pressure
  • Metabolic profile

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

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