First described by Wise in 1927, Woolly hair nevus is a rare, non hereditary anomaly caracterized by the presence of one or multiple patches of "woolly", uncombable hair, which is often lighter and finer than the rest of scalp hair. Mostly, the dermatosis manifests itself from birth or within the first years of life. In about 50% of cases, a linear epidermal nevus can be observed in the same site. Sporadic association with ocular and other ectodermal defects have been reported. Authors report two clinical cases and describe results of a morphologic and microanalytical comparative study conducted on the two patients' hair shafts. Light microscopy revealed the presence on affected hair shafts, of longitudinal grooves, swellings and twistings. Scanning electron microscopy confirmed the presence of depressions and longitudinal grooves and the absence of cuticolar anomalies. No alterations were observed on clinically unaffected hair. In both cases, microanalysis did not show relevant differences in the chemical composition of clinically affected hair in comparison to normal hair. This data should confirm the nevoid pathogenesis of this peculiar and rare anomaly.
|Translated title of the contribution||Woolly hair nevus: Ultrastructural and microanalytical study of hair shaft in two cases|
|Number of pages||4|
|Publication status||Published - Oct 1996|
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