@article{a040abf60bac45e8825863e87e33b482,
title = "Workload of breast image-guided intensity-modulated radiotherapy delivered with TomoTherapy",
abstract = "Objective: To report treatment times (door to door) of adjuvant treatments of breast cancer (BC) with intensity-modulated radiotherapy (IMRT). Methods: Treatment times of 62 patients with BC on the TomoTherapy Hi-Art System were collected for the analysis. Patients underwent either locoregional radiotherapy (postmastectomy radiotherapy [PMRT]) with helical modality (TomoHelical) or whole breast radiotherapy (RT) with simultaneous integrated boost (WBRT-SIB) with direct modality (TomoDirect). Door-to-door time was broken down into different steps, which were crucial to RT session. Results: A total of 594 treatment fractions were monitored. Median treatment time was 22.4 minutes (17.2–30.8) for PMRT and 14.4 minutes (10.9–23.5) for WBRT-SIB. The mean beam-on time accounted for 61.36% of the overall treatment time for PMRT compared to 57% for WBRT-SIB. The beam-on time was a much more time-consuming process. Conclusion: This treatment times analysis on the use of IMRT for BC might be useful to organize and improve the workflow efficiency in RT facilities. {\textcopyright} Fondazione IRCCS Istituto Nazionale dei Tumori 2019.",
keywords = "adjuvant radiotherapy, breast cancer, TomoTherapy, treatment time, adult, Article, brachial plexus, breast radiotherapy, breast reconstruction, cancer radiotherapy, clinical target volume, computer assisted tomography, controlled study, female, human, image registration, intensity modulated radiation therapy, major clinical study, mastectomy, planning target volume, supine position, time to treatment, tomotherapy, aged, breast tumor, cancer staging, disease management, image guided radiotherapy, middle aged, mortality, procedures, radiotherapy dosage, radiotherapy planning system, time factor, treatment outcome, very elderly, workload, Aged, Aged, 80 and over, Breast Neoplasms, Disease Management, Female, Humans, Middle Aged, Neoplasm Staging, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted, Radiotherapy, Adjuvant, Radiotherapy, Image-Guided, Radiotherapy, Intensity-Modulated, Time Factors, Treatment Outcome, Workload",
author = "R. Ricotti and E. Miglietta and M.C. Leonardi and F. Cattani and S. Dicuonzo and D.P. Rojas and G. Marvaso and R. Orecchia and B.A. Jereczek-Fossa",
note = "Cited By :1 Export Date: 5 March 2021 CODEN: TUMOA Correspondence Address: Leonardi, M.C.; Division of Radiation Oncology, Italy; email: cristina.leonardi@ieo.it Tradenames: Posiboard 2-Breastboard; TomoTherapy Hi-Art System Funding details: Accuray Funding text 1: This study was partially supported by a research grant from Accuray Inc. titled “Data collection and analysis of TomoTherapy and CyberKnife breast clinical studies, breast physics studies, and prostate study.” Funding text 2: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: M.C. Leonardi, B.A. Jereczek-Fossa, and F. Cattani received speaker honoraria from Accuray International. E. Miglietta and R. Ricotti received a research grant from Accuray Inc. (grant title: Data collection and analysis of TomoTherapy and CyberKnife breast clinical studies, breast physics studies, and prostate study). The sponsor, Accuray Inc., did not play any role in the study design, collection, analysis, or interpretation of data, or in the writing of the manuscript, or in the decision to submit the manuscript for publication. References: Orecchia, R., Rojas, D.P., Cattani, F., Hypofractionated postmastectomy radiotherapy with helical TomoTherapy in patients with immediate breast reconstruction: dosimetric results and acute/intermediate toxicity evaluation (2018) Med Oncol, 35, p. 39; Goddu, S.M., Chaudhari, S., Mamalui-Hunter, M., Helical TomoTherapy planning for left-sided breast cancer patients with positive lymph nodes: comparison to conventional multiport breast technique (2009) Int J Radiat Oncol Biol Phys, 73, pp. 1243-1251; Ashenafi, M., Boyd, R.A., Lee, T.K., Feasibility of postmastectomy treatment with helical TomoTherapy (2010) Int J Radiat Oncol Biol Phys, 77, pp. 836-842; Caudrelier, J.M., Morgan, S.C., Montgomery, L., Helical TomoTherapy for locoregional irradiation including the internal mammary chain in left-sided breast cancer: dosimetric evaluation (2009) Radiother Oncol, 90, pp. 99-105; Franco, P., Catuzzo, P., Cante, D., TomoDirect: an efficient means to deliver radiation at static angles with TomoTherapy (2011) Tumori, 97, pp. 498-502; Michalski, A., Atyeo, J., Cox, J., A dosimetric comparison of 3D-CRT, IMRT, and static TomoTherapy with an SIB for large and small breast volumes (2014) Med Dosim, 39, pp. 163-168; Franco, P., Zeverino, M., Migliaccio, F., Intensity-modulated and hypofractionated simultaneous integrated boost adjuvant breast radiation employing statics ports of TomoTherapy (TomoDirect): a prospective phase II trial (2014) J Cancer Res Clin Oncol, 140, pp. 167-177; Wolfson, D., Santa, J., Slass, L., Engaging physicians and consumers in conversations about treatment overuse and waste: a short history of the choosing wisely campaign (2014) Acad Med, 89, pp. 990-995; Smith, B.D., Bellon, J.R., Blitzblau, R., Radiation therapy for the whole breast: executive summary of an American Society for Radiation Oncology (ASTRO) evidence-based guideline (2018) Pract Radiat Oncol, 8, pp. 145-152; Ricotti, R., Ciardo, D., Fattori, G., Intra-fraction respiratory motion and baseline drift during breast helical TomoTherapy (2017) Radiother Oncol, 122, pp. 79-86; Reitz, D., Carl, G., Sch{\"o}necker, S., Real-time intra-fraction motion management in breast cancer radiotherapy: analysis of 2028 treatment sessions (2018) Radiat Oncol, 13, p. 128; Bijdekerke, P., Verellen, D., Tournel, K., TomoTherapy: implications on daily workload and scheduling patients (2008) Radiother Oncol, 86, pp. 224-230; Sterzing, F., Schubert, K., Sroka-Perez, G., Helical TomoTherapy: experiences of the first 150 patients in Heidelberg (2008) Strahlenther Onkol, 184, pp. 8-14; Piotrowski, T., Czajka, E., Bak, B., TomoTherapy: implications on daily workload and scheduling patients based on three years{\textquoteright} institutional experience (2014) Technol Cancer Res Treat, 13, pp. 233-242; Wojcieszynski, A.P., Olson, A.K., Rong, Y., Acute toxicity from breast cancer radiation using helical TomoTherapy with a simultaneous integrated boost (2016) Technol Cancer Res Treat, 15, pp. 257-265; Van Gestel, D., De Kerf, G., Wouters, K., Fast helical TomoTherapy in a head and neck cancer planning study: is time priceless? (2015) Radiat Oncol, 23, p. 261; Cao, Y.J., Lee, S., Chang, K.H., Patient performance-based plan parameter optimization for prostate cancer in TomoTherapy (2015) Med Dosim, 40, pp. 285-289; Yartsev, S., Kron, T., Van Dyk, J., TomoTherapy as a tool in image-guided radiation therapy (IGRT): theoretical and technological aspects (2007) Biomed Imaging Interv J, 3, p. e16",
year = "2020",
doi = "10.1177/0300891619868014",
language = "English",
volume = "106",
pages = "518--523",
journal = "Tumori",
issn = "0300-8916",
publisher = "SAGE Publications Ltd",
number = "6",
}