World federation of societies of biological psychiatry guidelines for the pharmacological treatment of dementias in primary care

Ralf Ihl, Robertas Bunevicius, Lutz Frölich, Bengt Winblad, Lon S. Schneider, Bruno Dubois, Alistair Burns, Florence Thibaut, Siegfried Kasper, Hans Jürgen Möller, Wioletta Baranska-Rybak, Wieclaw J. Cubala, Jaanus Harro, Victor J M Pop, Elmars Rancans, Jill Rasmussen, Zoltan Rihmer, Djea Saravane, Thomas E. Schlaepfer, Leo SherS. W. Tang, Leonas Valius, David Wong, Larisa M. Zhitnikova, Joseph Zohar, Michel Benoit, Rafael Blesa, Henry Brodaty, Nancy Colimon, Islwan Degrell, Steve DeKosky, Engin Eker, Hidetoshi Endo, Timo Erkinjuntti, Hans Förstl, Giovanni Frisoni, Serge Gauthier, Ezio Giacobini, Teresa Gomez-Isla, Carl Gerhard Goufries, Michael Grundman, Changsu Han, Christoph Hock, Isin Baral Kulaksizoglu, Josef Marksteiner, Colin Masters, Ian McKeith, Maria Olofsdottir, Michael Rainer, Barry Reisberg, Peter Riederer, Martin Rossor, Bernd Saletu, Eric Salmon, Trey Sunderland, Masatoshi Takeda, Bilgen Taneli, Bruno Vellas, Frans Verhey, Gunhild Waldemar, Peter Whitehouse

Research output: Contribution to journalReview articlepeer-review

Abstract

Objective. To define a practice guideline for biological treatment of dementias for general practitioners in primary care. Methods. TThis paper is a short and practical summary of the World Federation of Biological Psychiatry (WFSBP) guidelines for the Biological treatment of Alzheimer's disease and other dementias for treatment in primary care (Ihl et al. 2011). The recommendations were developed by a task force of international experts in the field and arc based on randomized controlled studies. Results. Anti-dementia medications neither cure, nor arrest, or alter the course of the disease. The type of dementia, the individual symptom constellation and the tolerability and evidence for efficacy should determine what medications should be used. In treating neuropsychiatrie symptoms, psychosocial intervention should be the treatment of first choice. For neuropsychiatrie symptoms, medications should only be considered when psychosocial interventions are not adequate and after cautious risk-benefit analysis. Conclusions. Depending on the diagnostic entity and clinical presentation different anti-dementia drugs can be recommended. These guidelines provide a practical approach for general practitioners managing dementias.

Original languageEnglish
Pages (from-to)2-7
Number of pages6
JournalInternational Journal of Psychiatry in Clinical Practice
Volume19
Issue number1
DOIs
Publication statusPublished - Mar 1 2015

Keywords

  • Alzheimer's disease
  • Anti-dementia drugs
  • Dementia
  • Guidelines
  • Lewy body disease
  • Neuropsychiatric symptoms

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Medicine(all)

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